Herbicidal pyridine N-oxide sulfonylureas

ABSTRACT

This invention relates to pyridine N-oxide sulfonylurea herbicides, agriculturally suitable compositions containing them and their method-of-use as preemergent and/or postemergent herbicides or plant growth regulants.

This is a division of application Serial No. 091,497, filed Aug. 31, 1987, now U.S. Pat. No. 4,789,465, which, in turn, is a continuation-in-part of Serial No. 929,980, filed Nov. 12, 1986, now abandoned.

BACKGROUND OF THE INVENTION

EP-A-13,480 discloses herbicidal sulfonamides of the formula ##STR1## wherein R₁ is H, Cl, Br, F, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ alkylthio, NO₂ or CO₂ R₅.

U.S. Pat. No. 4,339,267 discloses herbicidal sulfonamides of the formula ##STR2## wherein R₄ is H, Cl, Br, F, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, NO₂, CO₂ R₆ or SR₁₃.

U.S. Pat. No. 4,342,587 discloses herbicidal sulfonamides of the formula ##STR3## wherein B is Cl or Br.

U.S. Pat. No. 4,456,469 discloses herbicidal sulfonamides of the formula ##STR4## wherein R is C₁ -C₆ alkyl, C₃ -C₆ alkenyl, C₂ -C₄ alkoxyalkyl, C₅ -C₆ cycloalkyl, R'OCH₂ CH₂ OCH₂, ##STR5## and Z is H, F, Cl, Br, CH₃, OCH₃ or SCH₃.

U.S. Pat. No. 4,487,626 discloses herbicidal sulfonamides of the formula ##STR6## wherein A is ##STR7## and R₂ is H, F, Cl, Br, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, NO₂, CO₂ R₁₅, S(O)_(m) R₁₆, SO₂ NR₁₈ R₁₉ or SO₂ N(OCH₃)CH₃.

U.S. Pat. No. 4,421,550 discloses herbicidal sufonamides of the formula ##STR8## wherein Z is ##STR9## and R₁₆ is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, F, Cl, Br, CF₃, CO₂ R₂₀, SO₂ NR₁₀ R₁₁, SO₂ N(OCH₃)CH₃ or S(O)_(n) R₁₃.

U.S. Pat. No. 4,496,392 discloses herbicidal sulfonamides of the formula ##STR10## wherein R₃ is Cl, SO₂ CH₃ or SO₂ N(CH₃)₂.

EP-A-84,224 discloses herbicidal sulfonamides of the formula ##STR11## wherein A is ##STR12## and R₁₆ is H, C₁ --C₄ alkyl, C₁ --C₄ alkoxy, F, Cl, Br, CF₃, CO₂ R₉, SO₂ NR₁₀ R₁₁, SO₂ N(OCH₃)CH₃ or S(O)_(n) R₁₃.

EP-A-125,846 discloses herbicidal sulfonamides of the formula ##STR13## wherein J is ##STR14## and R is Cl, SO₂ CH₃, SO₂ N(CH₃)₂, OCH₃, NO₂ or N(CH₃)₂.

EP-A-155,767 discloses herbicidal sulfonamides of the formula ##STR15## wherein J is ##STR16## and R₅ is H, CH₃, Cl, Br, CO₂ R₁₅, C(O)NR₁₆ R₁₇, SO₂ NR₁₆ R₁₇, SO₂ N(OCH₃)CH₃, SO₂ R₁₈ or NO₂.

EP-A-161,905 discloses herbicidal sulfonamides of the formula ##STR17## wherein R₄ is CH₃, CH₂ CH₃, OCH₃, OCH₂ CH₃, F, Cl, Br, SO₂ NR₁₆ R₁₇, SO₂ N(OCH₃)CH₃, S(O)_(n) R₁₉, C₃ -C₄ alkenyloxy or C₃ -C₄ alkynyloxy.

EP-A-164,269 discloses herbicidal sulfonamides of the formula ##STR18## wherein R₄ is CH₃, CH₂ CH₃, OCH₃, OCH₂ CH₃, F, Cl, Br, SO₂ NR₁₁ R₁₂, SO₂ N(OCH₃)CH₃ or S(O)_(n) R₁₃.

EP-A-171,286 discloses herbicidal sulfonamides of the formula ##STR19## wherein R₄ is CH₃, CH₂ CH₃, OCH₃, OCH₂ CH₃, F, Cl, Br, SO₂ NR₁₈ R₁₉, SO₂ N(OCH₃)CH₃, S(O)_(n) R₂₁, C₃ -C₄ alkenyloxy, CH₂ OCH₃ or CH₂ OCH₂ CH₃.

EP-A-187,489 discloses herbicidal sulfonamides of the formula ##STR20## wherein L is ##STR21## Q is an optionally substituted 3- or 4-membered ring; and W is substituted alkenyl or alkynyl.

SUMMARY OF THE INVENTION

This application pertains to novel compounds of Formula I, agriculturally suitable compositions containing them and their method-of-use as preemergent and/or postemergent herbicides or plant growth regulants. ##STR22## wherein J is ##STR23## wherein R is H or CH₃ ;

E is a single bond or CH₂ ;

W is O, S or NR_(x) ;

R_(x) is H, C₁ -C₃ alkyl or C₁ -C₃ alkoxy;

R₁ is H, F, Cl, Br, C₁ -C₃ alkyl, C₁ -C₃ haloalkyl, C₁ -C₃ alkoxy, C₁ -C₃ haloalkoxy or C₁ -C₃ thioalkyl;

R₂ is H, Cl, Br, F, C₁ -C₄ alkyl, C₁ -C₄ haloalkyl, cyclopropyl optionally substituted by 1-4 halogen, cyclobutyl optionally substituted by 1-4 halogen, C₂ -C₄ alkenyl optionally substituted by halogen, C₂ -C₄ alkynyl optionally substituted by halogen, C₁ -C₄ alkoxy, C₁ -C₄ haloalkoxy, C₃ -C₄ alkenyloxy, C₃ -C₄ alkynyloxy, NO₂, CO₂ R₃, NR₄ R₅, S(O)_(n) R₆, SO₂ NR₇ R₈, C(O)NR₉ R₁₀, ##STR24## n is 0, 1 or 2; R₃ is C₁ -C₃ alkyl, C₂ -C₃ haloalkyl,

C₁ -C₃ alkoxy, C₃ -C₄ alkenyl, CH₂ (C₃ -C₅ cycloalkyl) or C₃ -C₄ alkynyl;

R₄ is H or C₁ -C₂ alkyl;

R₅ is C₁ -C₂ alkyl;

R₆ is C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₂ -C₄ alkoxyalkyl or C₁ -C₃ haloalkyl;

R₇ is H or C₁ -C₂ alkyl;

R₈ is C₁ -C₂ alkyl or C₁ -C₂ alkoxy;

R₉ is H or C₁ -C₃ alkyl;

R₁₀ is C₁ -C₃ alkyl;

R₁₁ is H or CH₃ ;

R₁₂ is H or CH₃ ;

R₁₃ is H, C₁ -C₃ alkyl, allyl, C₁ -C₃ haloalkyl or C₁ -C₃ alkyl substituted with C₁ -C₂ alkoxy;

R₁₃ ' is H, C₁ -C₃ alkyl, C₁ -C₃ haloalkyl, allyl, C₁ -C₂ alkoxy, C₁ -C₂ haloalkoxy or C₁ -C₂ alkylthio;

R₁₃ " is H, C₁ -C₃ alkyl, allyl or C₁ -C₃ haloalkyl;

R₁₄ is C₁ -C₃ alkyl, CH₂ OCH₃ or CH₂ CN:

A is ##STR25## X is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ haloalkoxy, C₁ -C₄ haloalkyl, C₁ -C₄ haloalkylthio, C₁ -C₄ alkylthio, halogen, C₂ -C₅ alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁ -C₃ alkylamino or di(C₁ -C₃ alkyl)amino;

Y is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ haloalkoxy, C₁ -C₄ haloalkylthio, C₁ -C₄ alkylthio, C₂ -C₅ alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁ -C₃ alkylamino, di(C₁ -C₃ alkyl)amino, C₃ -C₄ alkenyloxy, C₃ -C₄ alkylnyloxy, C₂ -C₅ alkylthioalkyl, C₂ -C₅ alkylsulfinylalkyl, C₂ -C₅ alkylsulfonylalkyl, C₁ -C₄ haloalkyl, C₂ -C₄ alkynyl, C₃ -C₅ cycloalkyl, azido, cyano, ##STR26## m is 2 or 3; Q₁ and Q₂ are independently O or S;

R_(a) is H or C₁ -C₃ alkyl;

R_(b) and R_(c) are independently C₁ -C₃ alkyl;

Z is CH, N, CCH₃, CC₂ H₅, CCl or CBr;

Y₁ is O or CH₂ ;

X₁ is CH₃, OCH₃, OC₂ H₅ or OCF₂ H;

X₂ is CH₃, C₂ H₅ or CH₂ CF₃ ;

Y₂ is OCH₃, OC₂ H₅, SCH₃, SC₂ H₅, CH₃ or CH₂ CH₃ ;

X₃ is CH₃ or OCH₃ ;

Y₃ is H or CH₃ ;

X₄ is CH₃, OCH₃, OC₂ H₅, CH₂ OCH₃ or Cl;

Y₄ is CH₃, OCH₃,OC₂ H₅ or Cl;

and their agriculturally suitable salts; provided that

(1) when X is halogen, then Z is CH and Y is OCH₃, OC₂ H₅, NH₂, NHCH₃, N(CH₃)₂, OCF₂ H, OCF₂ Br or N(OCH₃)CH₃ ;

(2) when X or Y is C₁ haloalkoxy, then Z is CH;

(3) when W is S, then R is H, E is a single bond, A is A-1, Z is CH or N, and Y is CH₃, OCH₃, OC₂ H₅, CH₂ OCH₃, C₂ H₅, CF₃, SCH₃, OCH₂ CH═CH₂. OCH₂ C.tbd.CH, OCH₂ CH₂ OCH₃, CH(OCH₃)₂ or ##STR27## (4) when the total number of carbon atoms of X and Y is greater than four, then the combined number of carbons of R₁ and R₂ is less than or equal to six; and

(5) X₄ and Y₄ are not simultaneously Cl.

In the above definitions, the term "alkyl", used either alone or in compound words such as "alkylthio" or "haloalkyl", denotes straight chain or branched alkyl, e.g., methyl, ethyl, n-propyl, isopropyl or the different butyl isomers.

Alkoxy denotes methoxy, ethoxy, n-propoxy, isopropoxy and the different butoxy isomers.

Alkenyl denotes straight chain or branched alkenes, e.g., vinyl, 1-propenyl, 2-propenyl, 3-propenyl and the different butenyl isomers.

Alkynyl denotes straight chain or branched alkynes, e.g., ethynyl, 1-propynyl, 2-propynyl and the different butynyl isomers.

The term "halogen", either alone or in compound words such as "haloalkyl", denotes fluorine, chlorine, bromine or iodine. Further, when used in compound words such as "haloalkyl" said alkyl may be monohalogenated or fully substituted with halogen atoms, which may be the same or different. Examples of haloalkyl include CH₂ CH₂ F, CF₂ CF₃ and CH₂ CHFCl.

Similarly, the terms haloalkoxy and haloalkylthio would include groups which are mono- or poly-substituted with halogen atoms, which may be the same or different.

The total number of carbon atoms in a substituent group is indicated by the C_(i) -C_(j) prefix where i and j are numbers from 1 to 5. For example, C₂ -C₄ alkenyl would designate ethenyl through butenyl.

Preferred for reasons of increased ease of synthesis and/or greater herbicidal efficacy are:

1. Compounds of Formula I where

X is C₁ -C₂ alkyl, C₁ -C₂ alkoxy, Cl, F, Br, I, OCF₂ H, CH₂ F, CF₃, OCH₂ CH₂ F, OCH₂ CHF₂, OCH₂ CF₃, CH₂ Cl or CH₂ Br; and

Y is H, C₁ -C₂ alkyl, C₁ -C₂ alkoxy, CH₂ OCH₃, CH₂ OCH₂ CH₃, NHCH₃, N(OCH₃)CH₃, N(CH₃)₂, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, OCH₂ CH₂ OCH₃, CH₂ SCH₃, C(O)R_(a), ##STR28## Z is CH or N; and R_(a) is H or CH₃.

2. Compounds of Preferred 1 where

E is a single bond;

W is O; and

R₁ is H, F, Cl, Br, CH₃, C₁ haloalkyl or OCH₃.

3. Compounds of Preferred 1 where

E is CH₂ ;

W is O; and

R₁ is H, F, Cl, Br, CH₃ or OCH₃.

4. Compounds of Preferred 2 where

R₂ is H, Cl, Br, F, C₁ -C₂ alkyl, C₁ -C₂ haloalkyl, cyclopropyl, C₁ -C₂ alkoxy, C₁ -C₂ haloalkoxy, CF═CFCl, CF═CFCF₃, NO₂, CO₂ R₃, NR₄ R₅, S(O)_(n) R₆, SO₂ NR₇ R₈, SO₂ N(OCH₃)CH₃, C(O)NR₉ R₁₀, R₂ -A, R₂ -B, R₂ -E, R₂ -J, R₂ -N, R₂ -Q, R₂ -R, R₂ -X, R₂ -Y, R₂ -AB, R₂ -AC or R₂ -AD;

R₃ is CH₃, CH₂ CH₃, CH₂ CH₂ OCH₃ or CH₂ CH₂ Cl;

R₄ is H or CH₃ ;

R₆ is C₁ -C₃ alkyl, C₁ -C₃ haloalkyl or allyl;

R₇ is H or CH₃ ;

R₈ is C₁ -C₂ alkyl

R₉ is H or CH₃ ;

R₁₀ is CH₃ or CH₂ CH₃ ;

R₁₃ is H, CH₃, CH₂ CH₃ or CH₂ CH₂ OCH₃ ; and

R₁₃ " is H, CH₃ or CH₂ CH₃.

5. Compounds of Preferred 4 where

X is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ;

Y is CH₃, OCH₃, CH₂ CH₃, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.

6. Compounds of Preferred 5 where

J is J₁ ; and

A is A-1.

7. Compounds of Preferred 5 where

J is J₂ ; and

A is A-1.

8. Compounds of Preferred 5 where

J is J₃ ; and

A is A-1.

9. Compounds of Preferred 5 where

J is J₄ ; and

A is A-1.

Specifically preferred for reasons of greatest ease of synthesis and/or greatest herbicidal efficacy are:

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-3-methyl-2-pyridinesulfonamide-1-oxide, m.p. 155°-157° C.; and

N[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)aminocarbonyl]-2-pyridinesulfonamide-1-oxide, m.p. 172°-176° C.

DETAILED DESCRIPTION OF THE INVENTION

Synthesis

Compounds of Formula I can be prepared by one or more of the procedures shown in Equations 1, 4, and 5. J, R, and A are as previously defined. ##STR29##

The reaction of Equation 1 is best carried out in an inert aprotic organic solvent such as dichloromethane, 1,2-dichloroethane, tetrahydrofuran, or acetonitrile, at a temperature between 20° C. and 85° C. The order of addition is not critical; however, it is often convenient to add the sulfonyl isocyanate or a solution of it in the reaction solvent, to a stirred suspension of the amine.

In some cases, the desired product is insoluble in the reaction solvent at ambient temperature and crystallizes from it in pure form. Products soluble in the reaction solvent are isolated by evaporation of the solvent. Compounds of Formula I then may be purified by trituration of the evaporation residue with solvents such as 1-chlorobutane or ethyl ether and filtration, by recrystallization from mixtures of solvents such as 1,2-dichloroethane, 1-chlorobutane and heptane or by chromatography on silica gel.

Sulfonyl isocyanates (II, W is O) are known in the art and are prepared from the corresponding sulfonamides (IV) by one of the following two general methods. ##STR30##

The sulfonamide IV is reacted with an alkyl isocyanate (e.g., n-butyl isocyanate) in a solvent whose boiling point is above 135° C., such as xylene. The reaction can optionally be carried out in the presence of a catalytic amount of 1,4-diaza[2.2.2]bicyclooctane (DABCO). The reaction mixture is heated to 135°-140° C. and held at that temperature for 5-60 minutes, after which phosgene is slowly added at such a rate that the temperature remains between 133° and 135° C. When the consumption of phosgene has ceased, the mixture is cooled and filtered to remove insoluble material. Finally, the solvent, alkyl isocyanate, and excess phosgene are evaporated, leaving the sulfonyl isocyanate (II).

If desired, the alkyl isocyanate-sulfonamide adduct can be made and isolated before reaction with the phosgene. In this case the sulfonamide (IV), alkyl isocyanate, and anhydrous base (e.g. K₂ CO₃) in a polar, aprotic solvent (e.g. acetone, butanone, or acetonitrile) are mixed and heated under reflux for 1 to 6 hours. The reaction mixture is then diluted with water, and the pH is adjusted to about 3 with acid (e.g. HCl, H₂ SO₄). The adduct is filtered out and dried, and then reacted with phosgene as described above. This procedure modification is especially useful when sulfonamide (IV) is high melting and has low solubility in the phosgenation solvent.

Sulfonyl isocyanates (II, W is O) can also be prepared by the following method. ##STR31##

The sulfonamide (IV) is heated at reflux in an excess of thionyl chloride. The reaction is continued until the sulfonamide protons are no longer detectable in the proton magnetic resonance spectrum. From 16 hours to 5 days is typically sufficient for complete conversion to the thionylamide (V) (Equation 3a).

The thionyl chloride is evaporated and the residue is treated with an inert solvent (e.g. toluene containing at least one equivalent (typically 2-3 equivalents) of phosgene. A catalytic amount of pyridine (typically 0.1 equivalent) is added, and the mixture is heated to about 60°-140° C. with 80°-100° C. preferred. Conversion to the isocyanate (II, W is O) is usually substantially complete within 15 minutes to 3 hours (Equation 3b). The mixture is then cooled and filtered, and the solvent is evaporated, leaving the sulfonyl isocyanate (II, W is O).

Sulfonyl isothiocyanates (II, W is S) are known in the art and are prepared from the corresponding sulfonamides (IV) by reaction with carbon disulfide and potassium hydroxide followed by treatment of the resulting dipotassiunm salt VI with phosgene. Such a procedure is described in Arch. Pharm. 299, 174 (1966).

Many of the compounds of Formula I can be prepared by the procedure shown in Equation 4. ##STR32##

The reaction of Equation 4 is carried out by contacting phenylcarbamates or phenylthiocarbamates of Formula VI with aminoheterocycles of Formula III in an inert organic solvent such as dioxane or tetrahydrofuran at temperatures of about 20°-100° C. for a period of about one-half to twenty-four hours. The product can be isolated by evaporation of the reaction solvent and purified by methods previously described.

Phenylcarbamates and phenylthiocarbamates of Formula VI can be prepared by the methods described, or modifications thereof known to those skilled in the art, in U.S. 4,443,243.

Alternatively, many of the compounds of Formula I can be prepared by the method described in Equation 5. ##STR33##

The reaction of Equation 5 can be carried out by contacting equimolar amounts of a sulfonamide of Formula IV with a heterocyclic phenylcarbamate or phenylthiocarbamate of Formula VII in the presence of a base such as 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU), by methods analogous to those described in South African Patent Application 83/0441. The phenylcarbamates and phenylthiocarbamates of Formula VII can be prepared by methods, or modifications thereof known to those skilled in the art, described in South African Patent Application 82/5671 and South African Patent Application 82/5045.

The sulfonamides IV of this invention may be prepared in a variety of ways, some of which are described in Equations 6 through 13.

For example, pyridine sulfonamides such as 1 may be oxidized directly to the corresponding N-oxide 2, using a variety of oxidants. Some of the oxidants of choice are m-chloroperoxybenzoic acid, CF₃ CO₃ H, H₂ O₂, etc. This is outlined in Equation 6. ##STR34##

In Equation 6, R₁ and R₂ are as previously defined, with the exception that R₂ cannot be a group which will react with a strong oxidant (i.e., thioalkyl, alkenyl, etc.). In addition, isomers of sulfonamide 2, that is sulfonamides such as 3, 4 and 5 may also be prepared in the same manner as outlined in Equation 6. ##STR35##

Preparation of pyridine sulfonamides such as 1 (and its isomers) is well known to one skilled in the art. For further details pertaining to the preparation of pyridine sulfonamides see, U.S. Pat. No. 4,544,401 (3-pyridine sulfonamides), U.S. Pat. No. 4,435,206 (2-pyridine sulfonamides), U.S. Pat. No. 4,456,469, U.S. Pat. No. 4,342,587 and EP-A-165,753.

Preparation of sulfonamides such as 2, 3, 4 and 5 may also be accomplished utilizing organo lithium chemistry as outlined in Equations 7 through 10. ##STR36##

The methodology outlined in Equations 7-10 is applicable to a wide variety of derivatives where R₁ and R₂ are compatible with organo metallic conditions. For example, sulfonamide 2a where R₁ is H and R₂ is CO₂ CH₃ may be prepared as outlined in Equation 11. ##STR37##

An alternate synthesis of sulfonamides such as 2, (also applicable to other isomers) is to introduce the n-oxide functionality into the pyridine ring at the beginning of the synthetic scheme rather than the end of the synthesis. This is outlined in Equation 12. ##STR38##

Preparation of sulfonamides such as 2 where R₂ is incompatible with reagents such as BuLi or LDA may be carried out in a variety of ways. for example, preparation of sulfonamides 10 and 12 utilizing fluoride 11 is outlined in Equation 13. ##STR39##

In Equation 13, introduction of the N-oxide functionality may be strategically done at any point of the synthesis. This then allows for the introduction of a functionality in R₂ which is sensitive to strong oxidants (i.e., thioalkyl, alkenyl, etc.) as discussed in Equation 6.

For further details pertaining to lithiations of pyridine ring systems see, Epsztarjn et al., Tetrahedron Lett., 4739 (1980): Snieckus et al., J. Am. Chem. Soc., 102, 1457 (1980); Kuraishi et al., Tet. Lett., 2049 (1983); Meyers et al., J. Org. Chem., 47, 2633 (1982); Taylor et al., J. Org. Chem., 48, 4156 (1983) and Breant et al., Synthesis, 822 (1983).

For further details pertaining to the oxidation of pyridines to pyridine N-oxides see, Evans et al., Rec. Trav., 78, 408 (1959).

For a general treatment of pyridines and pyridine N-oxides see, Katritzky, A. R., and Rees, C. W., "Comprehensive Heterocyclic Chemistry", Vol. 2, Pergamon Press, Oxford, N.Y., Part 2A, 1984.

The synthesis of heterocyclic amines such as those represented by Formula III has been reviewed in "The Chemistry of Heterocyclic Compounds," a series published by Interscience Publ., New York and London. Aminopyrimidines are described by D. J. Brown in "The Pyrimidines," Vol. XVI of the series mentioned above which is herein incorporated by reference. The 2-amino-1,3,5-triazines of Formula III, where A is A-1 and Z is N, can be prepared according to methods described by E. M. Smolin and L. Rapaport in "s-Triazines and Derivatives," Vol. XIII.

Pyrimidines of Formula III, where A is A-1 and Y is an acetal or thioacetal substituent, can be prepared by methods taught in European Patent Application No. 84,224 (published July 27, 1983).

Pyrimidines of Formula III, where A is A-1 and Y is cyclopropyl or OCF₂ H can be synthesized according to the methods taught in U.S. Pat. No. 4,515,626 and U.S. Pat. No. 4,540,782, respectively.

Compounds of Formula III, where A is A-2 or A-3, can be prepared by procedures disclosed in U.S. Pat. No. 4,339,267.

Compounds of Formula III, where A is A-4, can be prepared by methods taught in U.S. Pat. No. 4,487,626.

Additional references dealing with the synthesis of bicyclic pyrimidines of Formula III, where A is A-2, A-3, or A-4 are Braker, Sheehan, Spitzmiller and Lott, J. Am. Chem. Soc., 69, 3072 (1947); Mitler and Bhattachanya, Quart. J. Indian Chem. Soc., 4, 152 (1927); Dhrage and Hitchings, J. Org. Chem., 16, 1153 (1951); Caldwell, Kornfeld and Donnell, J. Am. Chem. Soc., 63, 2188 (1941); and Fissekis, Myles and Brown, J. Org. Chem., 29, 2670 (1964).

Compounds of Formula III, where A is A-5, can be prepared by methods taught in U.S. Pat. No. 4,421,550.

Compounds of Formula III, where A is A-6, can be prepared by methods taught in the U.S. Pat. No. 4,496,392.

Compounds of Formula III, where A is A-7 can be prepared by methods taught in EP-A-125,864.

Agriculturally suitable salts of compounds of Formula I are also useful herbicides and can be prepared in a number of ways known to the art. For example, metal salts can be made by contacting compounds of Formula I with a solution of an alkali or alkaline earth metal salt having a sufficiently basic anion (e.g., hydroxide, alkoxide, carbonate or hydroxide). Quaternary amine salts can be made by similar techniques.

Salts of compounds of Formula I can also be prepared by exchange of one cation for another. Cationic exchange can be effected by direct contact of an aqueous solution of a salt of a compound of Formula I (e.g., alkali or quaternary amine salt) with a solution containing the cation to be exchanged. This method is most effective when the desired salt containing the exchanged cation is insoluble in water and can be separated by filtration.

Exchange may also be effected by passing an aqueous solution of a salt of a compound of Formula I (e.g., an alkali metal or quaternary amine salt) through a column packed with a cation exchange resin containing the cation to be exchanged for that of the original salt and the desired product is eluted from the column. This method is particularly useful when the desired salt is water-soluble, e.g., a potassium sodium or calcium salt.

Acid addition salts, useful in this invention, can be obtained by reacting a compound of Formula I with a suitable acid, e.g., p-toluenesulfonic acid, trichloroacetic acid or the like.

The preparation of the compounds of this invention is further illustrated by the following specific examples. Unless otherwise indicated, temperatures are in degrees centigrade.

EXAMPLE 1 Preparation of 3-Methyl-2-(phenylmethylthio)pyridine

To a solution of NaH (2.4 g, 99 mmol) in 100 mL of DMF cooled to 0° C. is added benzylmercaptan (12.3 g, 99 mmol). The solution was allowed to warm to room temperature than recooled to 0° C. 2-Fluoro-3-methylpyridine in 10 mL DMF was added dropwise and stirred at room temperature overnight. The solution was diluted with H₂ O, extracted twice with Et₂ O, twice with EtOAc, and the combined organics washed twice with saturated NaHCO₃, dried and concentrated. The resulting oil was flash chromatographed (10% Et₂ O/hexane (v/v)) to yield 16.3 g of the desired product. NMR (200 MHz, CDCl₃) δ 2.24 (s, 3H), 4.50 (s, 2H), 6.9 (dd, 1H), 7.2 (m, 5H), 7.4 (d, 1H) and 8.3 (d, 1H).

EXAMPLE 2 Preparation of N-(1,1-Dimethylethyl)-3-methyl-2-pyridinesulfonamide

To a vigorously stirring mixture of 3-methyl-2-(phenylmethylthio)pyridine (25 g, 116 mmol) CH₂ Cl₂ (500 mL) and H₂ O (260 mL) cooled to 0° C. was added 45 mL of concentrated HCl. Chlorox® (500 mL) was then added dropwise between 0° to -5° C. The reaction was stirred 1 hour at 0° C. and then extracted with CH₂ Cl₂. The organic extracts were cooled to -70° C. and tert-butylamine (50 mL) was added dropwise. The solution was allowed to slowly warm to room temperature, diluted with H₂ O and extracted with CH₂ Cl₂. The organics were dried and concentrated to an oil. The oil was triturated with Et₂ O/hexane to afford 10 g of the desired product, m.p. 107°-110° C.; NMR (200 MHz, CDCl₃) δ 1.27 (s, 9H), 2.68 (s, 3H), 5.138 (br s, 1H), 7.35 (dd, 1H), 7.62 (d, 1H) and 8.4 (d, 1H).

EXAMPLE 3 Preparation of N-(1,1-Dimethylethyl)-3-methyl-2-pyridinesulfonamide-1-oxide

To a stirring solution of 3-methyl-2-tert-butylpyridinesulfonamide (3.2 g, 14.0 mmol) in 100 mL of CH₂ Cl₂ was added m-chloroperoxybenzoic acid (2.8 g, 14.0 mmol). The solution was stirred overnight at room temperature, washed once with brine, twice with saturated NaHCO₃, dried and concentrated. The resulting oil was flash chromatographed (25% EtOAc/hexane (v/v)) to yield 3.0 g of the desired product, m.p. 124°-126° C. NMR (200 MHz, CDCl₃) δ 1.25 (s, 9H), 2.7 (s, 3H), 7.1 (br s, 1H), 7.26 (m, 2H) and 8.2 (d, 1H).

EXAMPLE 4 Preparation of 3-Methyl-2-pyridinesulfonamide-1-oxide

A mixture of the N-oxide of N-(1,1-dimethylethyl)-3-methyl-2-pyridinesulfonamide (2.5 g, 8.2 mmol) and 50 mL of CF₃ CO₂ H were stirred for 6 hours. The CF₃ CO₂ H was removed under vacuun and the resulting solids were washed with butyl chloride to afford 1 g of the desired product, m.p. 233°-235° C., (M⁺ =188, expected, 188).

EXAMPLE 5 Preparation of N-[(4,6-Dimethylpyrimidin-2-yl)aminocarbonyl]-3-methyl-2-pyridinesulfonamide-1-oxide

To a stirring solution of the N-oxide of 3-methyl-2-pyridinesulfonamide (150 mg, 0.79 mmol) and the phenylcarbamate of 4,6-dimethyl-2-aminopyrimidine (194 mg, 0.79 mmol) in 3 mL of CH₃ CN was added DBU (121 mg, 0.79 mmol). The solution was stirred for 15 minutes. Three mL of H₂ O, then 3 mL of 5% HCl was added to the reaction and the resulting solid was collected,d m.p. 161°-163° C. NMR (200 MHz, d₆ -DMS0) δ 2,36 (s, 6H), 2.59 (s, 3H), 6.97 (s, 1H), 7.4 (d, 1H), 7.5 (d, 1H), 8.3 (d, 1H), 10.6 (br s, 1H) and 13.3 (br s, 1H).

EXAMPLE 6 Preparation of 3-Chloro-2-pyridinesulfnamide-1-oxide

To a stirring solution of 3-chloro-2-pyridinesulfonamide (2.5 g, 13.0 mmol) in 35 mL of trifluoroacetic acid was added 30% H₂ O₂ (1.2 g, 35.1 mmol). The solution was concentrated to ˜15 mL, diluted with ethyl acetate, washed twice with brine, dried and concentrated. The resulting solid was flash chromatographed with EtOAc to afford the desired product, m.p. 195°-197° C.

EXAMPLE 7 Preparation of 3-Chloro-N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-2-pyridinesulfonamide-1-oxide

To a stirring solution of the N-oxide of 3-chloro-2-pyridinesulfonamide (85 mg, 0.4 mmol) and the phenyl carbamate of 4,6-dimethoxy-2-aminopyrimidine (114 mg, 0.40 mmol) in acetonitrile was added DBU (62 mg, 0.40 mmol). Addition of H₂ O followed by 5% HCl caused a precipitate to form which was collected, m.p. 144°-147° C. NMR (200 MHz, d₆ -DMSO) δ 3.91 (s, 6H), 5.998 (s, 1H), 7.7 (m, 2H), 8.4 (d, 1H), 10.8 (br s, 1H) and 13.1 (br s, 1H); IR (nujol) 1710 (s) cm⁻¹ ; mass spectrum m/e 390 (M⁺, calc. for C₁₂ H₁₂ ClN₅ O₆ S 389+1).

EXAMPLE 8 Preparation of 6-methylthio-3-carboxy-2-pyridinesulfonamide-1-oxide methyl ester

To a stirring solution of n-butyllithium in 150 ml of tetrahydrofuran cooled to -78° C. was added 6-methylthio-2-pyridine-t-butylsulfonamide-1-oxide (30 g, 10.9 mmol) dropwise. The solution was stirred for one hour at -78° C. followed by dropwise addition of methylchloroformate (5.1 g, 53.4 mmol). The solution was warmed to 0° C. and quenched with brine. The organic layer was separated, dryed and concentrated to an oil. The resulting oil was subjected to MPLC with a 25% EtOAc-hexane (v/v) to afford 710 mg of product. This was then submitted to trifuloroacetic acid (25 ml) for 24 hours. Removal of the acid and triteration with BuCl afforded 400 mg of the desired sulfonamide: m.p. 199-202; NMR (200 MHz, DMSO) δ 2.48 (s, 3H), 3.78 (s, 3H), 7.60 (q, 2H), 7.90 (br s, 2H): mass spectrum m/e 279 (M⁺ , calc. for C₈ H₁₀ NO₅ S₂ 278+1).

    ______________________________________                                         COMPOUND TABLES                                                                Structure of J Substituent                                                     in Tables I-IV                                                                 ______________________________________                                         Table I J is J-1                                                                            ##STR40##                                                         Table II J is J-2                                                                           ##STR41##                                                         Table III J is J-3                                                                          ##STR42##                                                          Table IV J is J-4                                                                          ##STR43##                                                         ______________________________________                                    

                                      TABLE I                                      __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X       Y       Z    m.p. (°          __________________________________________________________________________                                                            C.)                     H  A-1 -- O  H       H            CH.sub.3                                                                               CH.sub.3                                                                               CH   169-172                 H  A-1 -- O  H       H            CH.sub.3                                                                               OCH.sub.3                                                                              CH   173-175                 H  A-1 -- O  H       H            OCH.sub.3                                                                              OCH.sub.3                                                                              CH   179-183                 H  A-1 -- O  H       H            CH.sub.3                                                                               CH.sub.3                                                                               N    149-166                 H  A-1 -- O  H       H            CH.sub.3                                                                               OCH.sub.3                                                                              N    172-176                 H  A-1 -- O  H       H            OCH.sub.3                                                                              OCH.sub.3                                                                              N    167-170                 H  A-1 -- O  H       H            Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Cl           CH.sub.3                                                                               CH.sub.3                                                                               CH   147-149                 H  A-1 -- O  H       Cl           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Cl           OCH.sub.3                                                                              OCH.sub.3                                                                              CH   144-147                 H  A-1 -- O  H       Cl           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       Cl           CH.sub.3                                                                               OCH.sub.3                                                                              N    130-132                 H  A-1 -- O  H       Cl           OCH.sub.3                                                                              OCH.sub. 3                                                                             N                            H  A-1 -- O  H       Cl           Cl      OCH.sub.3                                                                              CH   162-164                 H  A-1 -- O  H       Br           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       Br           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       B            OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Br           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       Br           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       Br           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       Br           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       F            CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       F            CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       F            OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       F            CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       F            CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       F            OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       F            Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               CH   161-163                 H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              CH   150-152                 H  A-1 -- O  H       CH           CH.sub.3                                                                               OCH.sub.3                                                                              CH   155-157                 H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              N    130-132                 H  A-1 -- O  H       CH.sub.3     OCH.sub.3                                                                              OCH.sub.3                                                                              N    156-158                 H  A-1 -- O  H       CH.sub.3     Cl      OCH.sub.3                                                                              CH   160-162                 H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH   147-150                 H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH   158-160                 H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH   175-178                 H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N    179-181                 H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N    133-185                 H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH   181-183                 H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH   143-147                 H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH   189-191                 H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       (CH.sub.2).sub.4 CH.sub.3                                                                   OCH.sub.3                                                                              OCH.sub.3                                                                              CH   178-180                 H  A-1 -- O  H       CH.sub.2 Cl  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 Cl  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 Cl  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 Cl  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 Br  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 Br  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 F   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.3                                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH(F)CH.sub.3                                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(F)CH.sub.3                                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(F)CH.sub.3                                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(F)CH.sub.3                                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.3                                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.3                                                                               Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      CH.sub.3                                                                               OCH.sub. 3                                                                             N                            H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 H   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CF.sub.2 H   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CF.sub.2 H   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CF.sub.2 H   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CF.sub.2 H   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 H   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 H   Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       Cl.sub.2 H   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       Cl.sub.2 H   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Cl.sub.2 H   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Cl.sub.2 H   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       Cl.sub.2 H   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       Cl.sub.2 H   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       Cl.sub.2 H   Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH(F)CH.sub.3                                                                      CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CH(F)CH.sub.3                                                                      CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH(F)CH.sub.3                                                                      OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3)CH(Cl)CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(CH.sub.3)CH(Cl)CH.sub.3                                                                  CH.sub. 3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 Br                                                                     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 Br                                                                     Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               CH   167-169                 H  A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              CH   146-148                 H  A-1 -- O  H       cyclopropyl  OCH.sub.3                                                                              OCH.sub.3                                                                              CH   178-180                 H  A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       cyclopropyl  OCH.sub.3                                                                              OCH.sub.3                                                                              N    182-184                 H  A-1 -- O  H       cyclopropyl  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR44##   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR45##   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR46##   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR47##   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR48##   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR49##   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR50##   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR51##   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR52##   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR53##   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR54##   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR55##   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR56##   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR57##   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR58##   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR59##   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR60##   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR61##   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR62##   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR63##   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR64##   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       cyclobutyl   CH      CH.sub.3                                                                               CH                           H  A-1 -- O  H       cyclobutyl   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       cyclobutyl   OCH     OCH.sub.3                                                                              CH                           H  A-1 -- O  H       cyclobutyl   CH      CH      N                            H  A-1 -- O  H       cyclobutyl   CH      OCH.sub.3                                                                              N                            H  A-1 -- O  H       cyclobutyl   OCH.sub.3                                                                              OCH     N                            H  A-1 -- O  H       cyclobutyl   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               OCH.sub. 3                                                                             CH                           H  A-1 -- O  H       CHCH.sub.2   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CHCH.sub.2   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CHCH.sub.2   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CFCH.sub.2                                                                          CH.sub.3                                                                               CH      CH                           H  A-1 -- O  H       CH.sub.2CFCH.sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHFCH.sub.2  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHFCH.sub.2  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CHFCH.sub.2  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CHFCH.sub.2  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2CCHCH.sub.3                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               OCH.sub. 3                                                                             CH                           H  A-1 -- O  H       CHCH.sub.2   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CHCH.sub.2   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CHCH.sub.2   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CCH CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CCH CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CCH OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CCH CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 CCH CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 C CH                                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CCH Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CCH          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CCH          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CCH          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CCH          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CCH          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CCH          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CCCH.sub.2 F Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CCCH.sub.2 F CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CCCH.sub.2 F CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CCCH.sub.2 F OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CCCH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2CCCH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2CCCH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2CCCH.sub.2 Cl                                                                       Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.3    CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.3    CH.sub.3                                                                               OCH.sub. 3                                                                             CH                           H  A-1 -- O  H       OCH.sub.3    OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.3    CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.3    CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.3    OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.3    Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 H  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCF.sub.2 H  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 H  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 H  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCF.sub.2 H  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCF.sub.2 H  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCF.sub.2 H  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub. 2 Cl                                                                      Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Br                                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Br                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Br                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Br                                                                       Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CCH CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2C CH                                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CCH OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CCH CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2CCH CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CCH OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CCH Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CHCH.sub.2                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       NO.sub.2     Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub. 3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub. 2 CH.sub.3                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub. 2 CHCH.sub.2                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2C CH                                                                       Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.3    CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SCH.sub.3    CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.3    OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.3    CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SCH.sub.3    CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.3    OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.3    Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SCH.sub. 2 CH.sub.3                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         OCH.sub.3                                                                              OCH.sub. 3                                                                             CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub. 3)CH.sub.2 CH.sub.3                                                      Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CONHCH.sub.3 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CONHCH.sub.3 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CONHCH.sub.3 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CONHCH.sub.3 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CONHCH.sub.3 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CONHCH.sub.3 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CONHCH.sub.3 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CONHCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR65##   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR66##   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR67##   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR68##   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR69##   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR70##   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR71##   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR72##   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR73##   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR74##   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR75##   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR76##   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR77##   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR78##   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR79##   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR80##   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR81##   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR82##   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR83##   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR84##   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR85##   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR86##   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR87##   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR88##   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR89##   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR90##   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR91##   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR92##   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR93##   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR94##   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR95##   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR96##   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR97##   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR98##   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR99##   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR100##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR101##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR102##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR103##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR104##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR105##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR106##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR107##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR108##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR109##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR110##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR111##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR112##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR113##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR114##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR115##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR116##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR117##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR118##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR119##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR120##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.3     OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.3     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.3     Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR121##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR122##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR123##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR124##  CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR125##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR126##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR127##  Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR128##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR129##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR130##  OCH.sub.3                                                                              OCH.sub. 3                                                                             CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR131##  CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR132##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR133##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR134##  Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR135##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR136##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR137##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR138##  CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR139##  CH.sub. 3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR140##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR141##  Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               OCH.sub. 3                                                                             CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       NO.sub. 2    Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub. 3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2C CH                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-F     CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     CH.sub.3     OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     CH.sub.3     CH.sub.3                                                                               CH.sub. 3                                                                              N                            H  A-1 -- O  6-F     CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     CH.sub.3     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     CH.sub.3     Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-F     CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-F     CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     CH.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-F     CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     CH(CH.sub.3).sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     CH(CH.sub.3).sub.2                                                                          CH.sub. 3                                                                              CH.sub.3                                                                               N                            H  A-1 -- O  6-F     CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     CH(CH.sub.3).sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     CH(CH.sub.3).sub.2                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     CH.sub.2 CH.sub.2 CH.sub.2                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-F     CH.sub.2 CH.sub.2 CH.sub.2                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     CH(CH.sub.3)CH.sub.2 CH.sub.2                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     CH(CH.sub.3)CH.sub.2 CH.sub.2                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-F     CH.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     CH.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     CH.sub.2 CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-Cl    cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-Cl    cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-Cl    cyclopropyl  OCH.sub.3                                                                              OCH.sub. 3                                                                             CH                           H  A-1 -- O  6-Cl    cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-Cl    cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-Cl    cyclopropyl  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-Cl    cyclopropyl  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-Cl                                                                                    ##STR142##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-Cl                                                                                    ##STR143##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-Cl                                                                                    ##STR144##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-Cl                                                                                    ##STR145##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-Cl                                                                                    ##STR146##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-Cl                                                                                    ##STR147##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-Cl                                                                                    ##STR148##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-Cl                                                                                    ##STR149##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-Cl                                                                                    ##STR150##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-Cl                                                                                    ##STR151##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-Cl                                                                                    ##STR152##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-Cl                                                                                    ##STR153##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-Cl                                                                                    ##STR154##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-Cl                                                                                    ##STR155##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-Cl                                                                                    ##STR156##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-Cl                                                                                    ##STR157##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-Cl                                                                                    ##STR158##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-Cl                                                                                    ##STR159##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-Cl                                                                                    ##STR160##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-Cl                                                                                    ##STR161##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-Cl                                                                                    ##STR162##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub. 3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Br                                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Br                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Br                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Br                                                                       Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CCH CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2C CH                                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CCH OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CCH CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CCH CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CCH OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CCH Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-CH.sub.3                                                                             NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-CH.sub.3                                                                             NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             NO.sub.2     Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub. 3                                                                              CH.sub.3                                                                               CH                           H  A-1 -- O  6-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub. 2 CH.sub.2 Cl                                                              Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub. 2 CF.sub.3                                                                  CO.sub.2 CH.sub.2 OCH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  4-SOCH.sub.3                                                                           H            CH.sub.3                                                                               CH.sub.3                                                                               CH   175-178                 H  A-1 -- O  4-SOCH.sub.3                                                                           H            CH.sub.3                                                                               OCH.sub.3                                                                              CH   163-166                 H  A-1 -- O  4-SOCH.sub.3                                                                           H            OCH.sub.3                                                                              OCH.sub.3                                                                              CH   214-217                 H  A-1 -- O  4-SOCH.sub.3                                                                           H            OCH.sub.3                                                                              CH.sub.3                                                                               N    170-172                 H  A-1 -- O  4-SOCH.sub.3                                                                           H            OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     SCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-F     SCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-F     SCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     SCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     SCH.sub.2CHCH.sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SCH.sub.2 CH.sub.2 OCH.sub.3                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-F     SCH.sub.2CCH CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SCH(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-F     SCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     SCH(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     SCH(CH.sub.3).sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SOCH.sub.3   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-F     SOCH.sub.3   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SOCH.sub.3   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SOCH.sub.3   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-F     SOCH.sub.3   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     SOCH.sub.3   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     SOCH.sub.3   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-F     SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-F     SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     SO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     SO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X       Y       Z    m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-1 -- O  6-SCH.sub.3                                                                            SCH.sub.3    CH.sub.3                                                                               CH.sub.3                                                                               CH   174-176                 H  A-1 -- O  6-SCH.sub.3                                                                            SCH.sub.3    CH.sub.3                                                                               OCH.sub.3                                                                              CH   169-171                 H  A-1 -- O  6-SCH.sub.3                                                                            H            CH.sub.3                                                                               CH.sub.3                                                                               CH   203-205                 H  A-1 -- O  6-SCH.sub.3                                                                            H            CH.sub.3                                                                               OCH.sub.3                                                                              CH   150-154                 H  A-1 -- O  6-SCH.sub.3                                                                            H            OCH.sub.3                                                                              OCH.sub.3                                                                              CH   189-192                 H  A-1 -- O  6-SCH.sub.3                                                                            H            CH.sub.3                                                                               OCH.sub.3                                                                              N    185-187                 H  A-1 -- O  6-SCH.sub.3                                                                            H            OCH.sub.3                                                                              OCH.sub.3                                                                              N    180-182                 H  A-1 -- O  6-SCH.sub.3                                                                            H            Cl      OCH.sub.3                                                                              CH   186-188                 __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.1 Y.sub.1      m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               O                                    H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.2                             H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              O                                    H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CH.sub.2                             H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.2 CH.sub.3                                                                     O                                    H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            CH.sub.2                             H  A-2 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               O                                    H  A-2 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  OCH.sub.3                                                                              O                                    H  A-2 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  OCF.sub.2 H                                                                            CH.sub.2                             __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.1              m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-3 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                     H  A-3 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                    H  A-3 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.2 CH.sub. 3                          H  A-3 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                  H  A-3 -- O  H       Cl           CH.sub.3                                     H  A-3 -- O  H       Cl           OCH.sub.3                                    H  A-3 -- O  H       SO.sub.2 CH.sub.3                                                                           CH.sub.3                                     H  A-3 -- O  H       SO.sub.2 CH.sub.3                                                                           OCH.sub.3                                    __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.1 Y.sub.3      m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               H                                    H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              H                                    H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.2 CH.sub.3                                                                     H                                    H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            H                                    H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                             H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CH.sub.3                             H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            CH.sub.3                             __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.2 Y.sub.2      m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                            H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.2 CH.sub.3                   H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.2 CH.sub.3                                                                     SCH.sub.3                            H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            SCH.sub.3 CH.sub.3                   H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                             H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.2 CH.sub.3                    H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 CH.sub.3                                                                      OCH.sub.3                            H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 CH.sub.3                                                                      SCH.sub.3                            H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                   H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 CF.sub.3                                                                      OCH.sub.3                            __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.3              m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-6 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                     H  A-6 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                    H  A-6 -- O  H       NO.sub.2     CH.sub.3                                     H  A-6 -- O  H       NO.sub.2     OCH.sub.3                                    __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.4 Y.sub.4      m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                             H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                            H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.2 CH.sub.3                   H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               Cl                                   H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CH.sub.3                             H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                            H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.2 CH.sub.3                                                                     OCH.sub.3                            __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X       Y       Z    m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCF.sub.2 H                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.2 OCH.sub.3                                                                     N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               SCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               SCF.sub.2 H                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               NHCH.sub.3                                                                             N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               N(CH.sub.3).sub.2                                                                      N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CCH     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               cyclopropyl                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CN      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CH.sub.2 CH.sub.3                                                                      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              SCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCF.sub.2 H                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub. 3                                                                          OCH.sub.3                                                                              CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              N(CH.sub.3).sub.2                                                                      N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              NHCH.sub.3                                                                             N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CN      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            CH.sub.2 CH.sub.3                                                                      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            SCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            N(CH.sub.3).sub.2                                                                      N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            NHCH.sub.3                                                                             N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub. 2 OCH.sub.3                                                                    OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     CH.sub.2 Cl                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     CH.sub.2 Br                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           SCF.sub.2 H                                                                            OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           SCF.sub.2 H                                                                            CH.sub.2 CH.sub.3                                                                      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           SCF.sub.2 H                                                                            CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           SCF.sub.2 H                                                                            NHCH.sub.3                                                                             N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           N(CH.sub.3).sub.2                                                                      OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           N(CH.sub.3).sub.2                                                                      CH.sub.2 CH.sub.3                                                                      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           N(CH.sub.3).sub.2                                                                      CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           N(CH.sub.3).sub.2                                                                      CH.sub.2 OCH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           N(CH.sub.3).sub.2                                                                      cyclopropyl                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CCH     CH.sub.2 CH.sub.3                                                                      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CCH     OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CCH     N(CH.sub.3).sub.2                                                                      N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CCH     OCH.sub.2 CH.sub.3                                                                     CH                           __________________________________________________________________________

                                      TABLE II                                     __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X       Y       Z    m.p. (°          __________________________________________________________________________                                                            C.)                     H  A-1 -- O  H       H            CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       H            CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       H            OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       H            CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       H            CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       H            OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       H            Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Cl           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       Cl           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Cl           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Cl           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       Cl           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       Cl           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       Cl           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Br           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       Br           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       B            OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Br           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       Br           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       Br           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       Br           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       F            CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       F            CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       F            OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       F            CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       F            CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       F            OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       F            Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.3     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.3     Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         OCH.sub.3                                                                              OCH.sub. 3                                                                             CH                           H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 Cl  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 Cl  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 Cl  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 Cl  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 Br  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 Br  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 F   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.3                                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH(F)CH.sub.3                                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(F)CH.sub.3                                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(F)CH.sub.3                                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(F)CH.sub.3                                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.3                                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.3                                                                               Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 H   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CF.sub.2 H   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CF.sub.2 H   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CF.sub.2 H   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CF.sub.2 H   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 H   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 H   Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       Cl.sub.2 H   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       Cl.sub.2 H   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Cl.sub. 2 H  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Cl.sub.2 H   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       Cl.sub.2 H   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       Cl.sub.2 H   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       Cl.sub.2 H   Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH(F)CH.sub.3                                                                      CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CH(F)CH.sub.3                                                                      CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH(F)CH.sub.3                                                                      OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3)CH(Cl)CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(CH.sub.3)CH(Cl)CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 Br                                                                     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 Br                                                                     Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       cyclopropyl  OCH.sub. 3                                                                             OCH.sub.3                                                                              CH                           H  A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       cyclopropyl  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       cyclopropyl  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR163##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR164##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR165##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR166##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR167##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR168##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR169##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR170##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR171##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR172##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR173##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR174##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR175##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR176##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR177##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR178##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR179##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR180##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR181##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR182##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR183##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       cyclobutyl   CH      CH.sub.3                                                                               CH                           H  A-1 -- O  H       cyclobutyl   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       cyclobutyl   OCH     OCH.sub.3                                                                              CH                           H  A-1 -- O  H       cyclobutyl   CH      CH      N                            H  A-1 -- O  H       cyclobutyl   CH      OCH.sub.3                                                                              N                            H  A-1 -- O  H       cyclobutyl   OCH.sub.3                                                                              OCH     N                            H  A-1 -- O  H       cyclobutyl   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          CH.sub. 3                                                                              CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHCH.sub.2   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CHCH.sub.2   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CHCH.sub.2   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CFCH.sub.2                                                                          CH.sub.3                                                                               CH      CH                           H  A-1 -- O  H       CH.sub.2CFCH.sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHFCH.sub.2  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHFCH.sub.2  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CHFCH.sub.2  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CHFCH.sub.2  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CHCHCH.sub.3                                                                       Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CCH  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2CCH  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CCH  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CCH  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2CCH  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2CCH  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2CCH  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CCH          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CCH          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CCH          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CCH          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CCH          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CCH          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CCCH.sub.2 F Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CCCH.sub.2 F CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CCCH.sub.2 F CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CCCH.sub.2 F OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CCCH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2CCCH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2CCCH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2CCCH.sub.2 Cl                                                                       Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.3    CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.3    CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.3    OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.3    CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.3    CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.3    OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.3    Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH(CH.sub.3).sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 H  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCF.sub.2 H  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 H  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 H  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCF.sub.2 H  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCF.sub.2 H  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCF.sub.2 H  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub. 3                                                                             N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub. 3                                                                              CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Br                                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Br                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Br                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Br                                                                       Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2C CH                                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2CCH CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CCH OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CCH CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2CCH CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CCH OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CCH Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       NO.sub.2     Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub. 2 F                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2C CH                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.3    CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SCH.sub.3    CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.3    OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.3    CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SCH.sub.3    CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.3    OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.3    Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub. 2 CH.sub.3).sub.2                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(OCH.sub. 3)CH.sub.3                                                              CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CONHCH.sub.3 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CONHCH.sub.3 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CONHCH.sub.3 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CONHCH.sub.3 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CONHCH.sub.3 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CONHCH.sub.3 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CONHCH.sub.3 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CONHCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR184##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR185##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR186##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR187##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR188##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR189##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR190##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR191##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR192##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR193##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR194##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR195##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR196##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR197##  Cl              CH                           H  A-1 -- O  H                                                                                       ##STR198##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR199##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR200##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR201##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR202##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR203##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR204##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR205##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR206##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR207##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR208##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR209##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR210##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR211##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR212##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR213##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR214##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR215##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR216##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR217##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR218##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR219##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR220##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR221##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR222##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR223##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR224##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR225##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR226##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR227##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR228##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR229##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR230##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR231##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR232##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR233##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR234##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR235##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR236##  CH.sub.3                                                                               CH.sub. 3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR237##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR238##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR239##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.3     OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.3     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.3     Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub. 3                                                                              CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR240##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR241##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR242##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR243##  CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR244##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR245##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR246##  Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR247##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR248##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR249##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR250##  CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR251##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR252##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR253##  Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR254##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR255##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR256##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR257##  CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR258##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR259##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR260##  Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub. 2 CF.sub.3                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     CH.sub. 3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                OCH.sub.3                                                                              OCH.sub. 3                                                                             CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2C CH                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-F     CH.sub.3     CH.sub.3                                                                               OCH.sub. 3                                                                             CH                           H  A-1 -- O  5-F     CH.sub.3     OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-F     CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     CH.sub.3     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     CH.sub.3     Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-F     CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-F     CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     CH.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-F     CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH(CH.sub.3).sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-F     CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     CH(CH.sub.3).sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     CH(CH.sub.3).sub.2                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH.sub.2 CH.sub.2 CH.sub.2                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-F     CH.sub.2 CH.sub.2 CH.sub.2                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH(CH.sub.3)CH.sub.2 CH.sub.2                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH(CH.sub.3)CH.sub.2 CH.sub.2                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-F     CH.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     CH.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     CH.sub.2 CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl    cyclopropyl  CH.sub. 3                                                                              CH.sub.3                                                                               CH                           H  A-1 -- O  5-Cl    cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl    cyclopropyl  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl    cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-Cl    cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-Cl    cyclopropyl  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-Cl    cyclopropyl  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl                                                                                    ##STR261##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-Cl                                                                                    ##STR262##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl                                                                                    ##STR263##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl                                                                                    ##STR264##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-Cl                                                                                    ##STR265##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-Cl                                                                                    ##STR266##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-Cl                                                                                    ##STR267##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl                                                                                    ##STR268##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-Cl                                                                                    ##STR269##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl                                                                                    ##STR270##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl                                                                                    ##STR271##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-Cl                                                                                    ##STR272##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-Cl                                                                                    ##STR273##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-Cl                                                                                    ##STR274##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl                                                                                    ##STR275##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-Cl                                                                                    ##STR276##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl                                                                                    ##STR277##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl                                                                                    ##STR278##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-Cl                                                                                    ##STR279##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-Cl                                                                                    ##STR280##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-Cl                                                                                    ##STR281##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub. 2 CH.sub.2 CH.sub.2 F                                                              CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Br                                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Br                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Br                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Br                                                                       Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2C CH                                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CCH CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CCH OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CCH CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CCH CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CCH OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CCH Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-OCH.sub.3                                                                            NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-OCH.sub.3                                                                            NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.3                                                                            NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.3                                                                            NO.sub.2     Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub. 3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.2 CH.sub.3                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  4-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  4-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     SCH.sub.2CH CH.sub.2                                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-F     SCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     SCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     SCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-F     SCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     SCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     SCH.sub.2CHCH.sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     SCH.sub.2 CH.sub.2 OCH.sub.3                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-F     SCH.sub.2CCH CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     SCH(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     SCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-F     SCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     SCH(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     SCH(CH.sub.3).sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     SOCH.sub.3   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-F     SOCH.sub.3   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     SOCH.sub.3   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     SOCH.sub.3   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-F     SOCH.sub.3   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     SOCH.sub.3   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     SOCH.sub.3   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-F     SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     SO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-F     SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     SO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     SO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.1 Y.sub.1      m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               O                                    H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.2                             H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              O                                    H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CH.sub.2                             H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.2 CH.sub.3                                                                     O                                    H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            CH.sub.2                             H  A-2 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               O                                    H  A-2 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  OCH.sub.3                                                                              O                                    H  A-2 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  OCF.sub.2 H                                                                            CH.sub.2                             __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.1              m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-3 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                     H  A-3 -- O  H       CO.sub.2 CH.sub. 3                                                                          OCH.sub.3                                    H  A-3 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.2 CH.sub.3                           H  A-3 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                  H  A-3 -- O  H       Cl           CH.sub.3                                     H  A-3 -- O  H       Cl           OCH.sub.3                                    H  A-3 -- O  H       SO.sub.2 CH.sub.3                                                                           CH.sub.3                                     H  A-3 -- O  H       SO.sub.2 CH.sub.3                                                                           OCH.sub.3                                    __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.1 Y.sub.3      m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               H                                    H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              H                                    H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.2 CH.sub.3                                                                     H                                    H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            H                                    H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                             H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CH.sub.3                             H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            CH.sub.3                             __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.2 Y.sub. 2     m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                            H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.2 CH.sub.3                   H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.2 CH.sub.3                                                                     SCH.sub.3                            H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            SCH.sub.3 CH.sub.3                   H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                             H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.2 CH.sub.3                    H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 CH.sub.3                                                                      OCH.sub.3                            H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 CH.sub.3                                                                      SCH.sub.3                            H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                   H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 CF.sub.3                                                                      OCH.sub.3                            __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.3              m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-6 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                     H  A-6 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                    H  A-6 -- O  H       NO.sub.2     CH.sub.3                                     H  A-6 -- O  H       NO.sub.2     OCH.sub.3                                    __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.4 Y.sub.4      m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                             H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                            H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.2 CH.sub.3                   H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               Cl                                   H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CH.sub.3                             H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                            H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.2 CH.sub.3                                                                     OCH.sub.3                            __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X       Y       Z    m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCF.sub.2 H                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               SCF.sub.2 H                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               SCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.2 OCH.sub.3                                                                     N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               NHCH.sub.3                                                                             N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               N(CH.sub.3).sub.2                                                                      N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CCH     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               cyclopropyl                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CN      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CH.sub.2 CH.sub.3                                                                      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              SCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub. 3                                                                          OCH.sub.3                                                                              OCF.sub.2 H                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              N(CH.sub.3).sub.2                                                                      N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              NHCH.sub.3                                                                             N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CN      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            CH.sub.2 CH.sub.3                                                                      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            SCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            N(CH.sub.3).sub.2                                                                      N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            NHCH.sub.3                                                                             N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     CH.sub.2 Cl                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     CH.sub.2 Br                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           SCF.sub.2 H                                                                            OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           SCF.sub.2 H                                                                            CH.sub.2 CH.sub.3                                                                      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           SCF.sub.2 H                                                                            CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           SCF.sub.2 H                                                                            NHCH.sub.3                                                                             N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           N(CH.sub.3).sub.2                                                                      OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           N(CH.sub.3).sub.2                                                                      CH.sub.2 CH.sub.                                                                       CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           N(CH.sub.3).sub.2                                                                      CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           N(CH.sub.3).sub.2                                                                      CH.sub.2 OCH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           N(CH.sub.3).sub.2                                                                      cyclopropyl                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CCH     CH.sub.2 CH.sub.3                                                                      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CCH     OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CCH     N(CH.sub.3).sub.2                                                                      N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CCH     OCH.sub.2 CH.sub.3                                                                     CH                           __________________________________________________________________________

                                      TABLE III                                    __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X       Y       Z    m.p. (°          __________________________________________________________________________                                                            C.)                     H  A-1 -- O  H       H            CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       H            CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       H            OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       H            CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       H            CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       H            OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       H            Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Cl           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       Cl           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Cl           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Cl           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       Cl           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       Cl           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       Cl           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Br           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       Br           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       B            OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Br           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       Br           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       Br           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       Br           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       F            CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       F            CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       F            OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       F            CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       F            CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       F            OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       F            Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.3     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.3     Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         OCH.sub.3                                                                              OCH.sub. 3                                                                             CH                           H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 Cl  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 Cl  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 Cl  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 Cl  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 Br  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 Br  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 F   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.3                                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH(F)CH.sub.3                                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(F)CH.sub.3                                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(F)CH.sub.3                                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(F)CH.sub.3                                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.3                                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.3                                                                               Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 H   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CF.sub.2 H   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CF.sub.2 H   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CF.sub.2 H   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CF.sub.2 H   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 H   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 H   Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       Cl.sub.2 H   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       Cl.sub.2 H   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Cl.sub. 2 H  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Cl.sub.2 H   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       Cl.sub.2 H   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       Cl.sub.2 H   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       Cl.sub.2 H   Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH(F)CH.sub.3                                                                      CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CH(F)CH.sub.3                                                                      CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH(F)CH.sub.3                                                                      OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3)CH(Cl)CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(CH.sub.3)CH(Cl)CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 Br                                                                     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 Br                                                                     Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       cyclopropyl  OCH.sub. 3                                                                             OCH.sub.3                                                                              CH                           H  A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       cyclopropyl  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       cyclopropyl  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR282##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR283##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR284##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR285##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR286##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR287##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR288##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR289##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR290##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR291##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR292##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR293##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR294##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR295##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR296##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR297##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR298##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR299##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR300##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR301##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR302##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       cyclobutyl   CH      CH.sub.3                                                                               CH                           H  A-1 -- O  H       cyclobutyl   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       cyclobutyl   OCH     OCH.sub.3                                                                              CH                           H  A-1 -- O  H       cyclobutyl   CH      CH      N                            H  A-1 -- O  H       cyclobutyl   CH      OCH.sub.3                                                                              N                            H  A-1 -- O  H       cyclobutyl   OCH.sub.3                                                                              OCH     N                            H  A-1 -- O  H       cyclobutyl   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          CH.sub. 3                                                                              CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHCH.sub.2   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CHCH.sub.2   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CHCH.sub.2   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CFCH.sub.2                                                                          CH.sub.3                                                                               CH      CH                           H  A-1 -- O  H       CH.sub.2CFCH.sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHFCH.sub.2  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHFCH.sub.2  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CHFCH.sub.2  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CHFCH.sub.2  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2CCHCH.sub.3                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHCH.sub.2   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CHCH.sub.2   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CHCH.sub.2   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CCH CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CCH CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CCH OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CCH CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 CCH CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CCH OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CCH Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CCH          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       C CH         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CCH          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CCH          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CCH          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CCH          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CCCH.sub.2 F Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CCCH.sub.2 F CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CCCH.sub.2 F CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CCCH.sub.2 F OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CCCH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2CCCH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2CCCH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2CCCH.sub.2 Cl                                                                       Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.3    CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.3    CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.3    OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.3    CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.3    CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.3    OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.3    Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub. 3                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 H  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCF.sub.2 H  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 H  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 H  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCF.sub.2 H  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCF.sub. 2 H OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCF.sub.2 H  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 CH.sub. 3                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub. 2 Cl                                                                      CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Br                                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Br                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Br                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Br                                                                       Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CCH CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2CCH CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CCH OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CCH CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2C CH                                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CCH OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CCH Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       NO.sub.2     Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub. 2 CH.sub.2 OCH.sub.3                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub. 2 OCH.sub.3                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       N(CH.sub.3 ).sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.3    CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SCH.sub.3    CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.3    OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.3    CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SCH.sub.3    CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.3    OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.3    Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                OCH.sub. 3                                                                             OCH.sub.3                                                                              N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         Cl      OCH.sub. 3                                                                             CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CONHCH.sub.3 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CONHCH.sub.3 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CONHCH.sub.3 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CONHCH.sub.3 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CONHCH.sub.3 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CONHCH.sub.3 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CONHCH.sub.3 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CONHCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR303##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR304##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR305##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR306##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR307##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR308##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR309##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR310##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR311##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR312##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR313##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR314##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR315##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR316##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR317##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR318##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR319##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR320##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR321##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR322##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR323##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR324##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR325##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR326##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR327##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR328##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR329##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR330##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR331##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR332##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR333##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR334##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR335##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR336##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR337##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR338##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR339##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR340##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR341##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR342##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR343##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR344##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR345##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR346##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR347##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR348##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR349##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR350##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR351##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR352##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR353##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR354##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR355##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR356##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR357##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR358##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.3     OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.3     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.3     Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR359##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR360##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR361##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR362##  CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR363##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR364##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR365##  Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR366##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR367##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR368##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR369##  CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR370##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR371##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR372##  Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR373##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR374##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR375##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR376##  CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR377##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR378##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR379##  Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub. 2 CH.sub.2 Cl                                                                      CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub. 3                                                                             N                            CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  2-F     CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     CH.sub.3     OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  2-F     CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  2-F     CH.sub.3     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  2-F     CH.sub.3     Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  2-F     CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  2-F     CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  2-F     CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  2-F     CH.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  2-F     CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     CH(CH.sub.3).sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  2-F     CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  2-F     CH(CH.sub.3).sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  2-F     CH(CH.sub.3).sub.2                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     CH.sub.2 CH.sub.2 CH.sub.2                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  2-F     CH.sub.2 CH.sub.2 CH.sub.2                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     CH(CH.sub.3)CH.sub.2 CH.sub.2                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     CH(CH.sub.3)CH.sub.2 CH.sub.2                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  2-F     CH.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  2-F     CH.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  2-F     CH.sub.2 CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  2-Cl    cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  2-Cl    cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  2-Cl    cyclopropyl  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  2-Cl    cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  2-Cl    cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  2-Cl    cyclopropyl  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  2-Cl    cyclopropyl  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  2-Cl                                                                                    ##STR380##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  2-Cl                                                                                    ##STR381##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  2-Cl                                                                                    ##STR382##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  2-Cl                                                                                    ##STR383##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  2-Cl                                                                                    ##STR384##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  2-Cl                                                                                    ##STR385##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  2-Cl                                                                                    ##STR386##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  2-Cl                                                                                    ##STR387##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  2-Cl                                                                                    ##STR388##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  2-Cl                                                                                    ##STR389##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  2-Cl                                                                                    ##STR390##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  2-Cl                                                                                    ##STR391##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  2-Cl                                                                                    ##STR392##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  2-Cl                                                                                    ##STR393##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  2-Cl                                                                                    ##STR394##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  2-Cl                                                                                    ##STR395##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  2-Cl                                                                                    ##STR396##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  2-Cl                                                                                    ##STR397##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  2-Cl                                                                                    ##STR398##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  2-Cl                                                                                    ##STR399##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  2-Cl                                                                                    ##STR400##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Br                                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Br                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Br                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Br                                                                       Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CCH CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CCH CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CCH OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CCH CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2C CH                                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CCH OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CCH Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  2-CH.sub.3                                                                             NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  2-CH.sub.3                                                                             NO.sub.2     CH.sub. 3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  2-CH.sub.3                                                                             NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  2-CH.sub.3                                                                             NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  2-CH.sub.3                                                                             NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  2-CH.sub.3                                                                             NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  2-CH.sub.3                                                                             NO.sub.2     Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  2-CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  2-CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  2-CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  2-CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  2-CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  2-CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  2-CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  2-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub. 3                                                                              CH                           H  A-1 -- O  2-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  2-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  2-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  2-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  2-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  2-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  2-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  2-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  2-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  2-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  2-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  2-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  2-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  2-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     SCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  2-F     SCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     SCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     SCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  2-F     SCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  2-F     SCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  2-F     SCH.sub.2CHCH.sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     SCH.sub.2 CH.sub.2 OCH.sub.3                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  2-F     SCH.sub.2CCH CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     SCH(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     SCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  2-F     SCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  2-F     SCH(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  2-F     SCH(CH.sub.3).sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     SOCH.sub.3   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  2-F     SOCH.sub.3   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     SOCH.sub.3   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     SOCH.sub.3   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  2-F     SOCH.sub.3   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  2-F     SOCH.sub.3   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  2-F     SOCH.sub.3   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  2-F     SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     SO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  2-F     SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  2-F     SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  2-F     SO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  2-F     SO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.1 Y.sub.1      m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               O                                    H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.2                             H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              O                                    H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CH.sub.2                             H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.2 CH.sub.3                                                                     O                                    H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            CH.sub.2                             H  A-2 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               O                                    H  A-2 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  OCH.sub.3                                                                              O                                    H  A-2 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  OCF.sub.2 H                                                                            CH.sub.2                             __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.1              m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-3 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                     H  A-3 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                    H  A-3 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.2 CH.sub.3                           H  A-3 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                  H  A-3 -- O  H       Cl           CH.sub.3                                     H  A-3 -- O  H       Cl           OCH.sub.3                                    H  A-3 -- O  H       SO.sub.2 CH.sub.3                                                                           CH.sub.3                                     H  A-3 -- O  H       SO.sub.2 CH.sub.3                                                                           OCH.sub.3                                    __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.1 Y.sub.3      m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               H                                    H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              H                                    H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.2 CH.sub.3                                                                     H                                    H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            H                                    H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                             H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CH.sub.3                             H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            CH.sub.3                             __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.2 Y.sub.2      m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                            H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.2 CH.sub.3                   H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.2 CH.sub.3                                                                     SCH.sub.3                            H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            SCH.sub.3 CH.sub.3                   H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                             H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.2 CH.sub.3                    H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 CH.sub.3                                                                      OCH.sub.3                            H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 CH.sub.3                                                                      SCH.sub.3                            H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                   H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 CF.sub.3                                                                      OCH.sub.3                            __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.3              m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-6 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                     H  A-6 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                    H  A-6 -- O  H       NO.sub.2     CH.sub.3                                     H  A-6 -- O  H       NO.sub.2     OCH.sub.3                                    __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.4 Y.sub.4      m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                             H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                            H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.2 CH.sub.3                   H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               Cl                                   H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CH.sub.3                             H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                            H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.2 CH.sub.3                                                                     OCH.sub.3                            __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X       Y       Z    m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCF.sub.2 H                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               SCF.sub.2 H                                                                            CH                              A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               SCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.2 OCH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               NHCH.sub.3                                                                             N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               N(CH.sub.3).sub.2                                                                      N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               C CH    CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               cyclopropyl                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CN      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CH.sub.2 CH.sub.3                                                                      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              SCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCF.sub.2 H                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              N(CH.sub.3).sub.2                                                                      N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              NHCH.sub.3                                                                             N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CN      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            CH.sub.2 CH.sub.3                                                                      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            SCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            N(CH.sub.3).sub.2                                                                      N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            NHCH.sub.3                                                                             N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     CH.sub.2 Cl                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     CH.sub.2 Br                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           SCF.sub.2 H                                                                            OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           SCF.sub.2 H                                                                            CH.sub.2 CH.sub.3                                                                      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           SCF.sub.2 H                                                                            CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           SCF.sub.2 H                                                                            NHCH.sub.3                                                                             N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           N(CH.sub.3).sub.2                                                                      OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           N(CH.sub.3).sub.2                                                                      CH.sub.2 CH.sub.3                                                                      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           N(CH.sub.3).sub.2                                                                      CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           N(CH.sub.3).sub.2                                                                      CH.sub.2 OCH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           N(CH.sub.3).sub.2                                                                      cyclopropyl                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CCH     CH.sub.2 CH.sub.3                                                                      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CCH     OCH.sub. 3                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CCH     N(CH.sub.3).sub.2                                                                      N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CCH     OCH.sub.2 CH.sub.3                                                                     CH                           __________________________________________________________________________

                                      TABLE IV                                     __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X       Y       Z    m.p. (°          __________________________________________________________________________                                                            C.)                     H  A-1 -- O  H       H            CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       H            CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       H            OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       H            CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       H            CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       H            OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       H            Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Cl           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       Cl           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Cl           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Cl           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       Cl           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       Cl           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       Cl           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Br           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       Br           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       B            OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Br           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       Br           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       Br           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       Br           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       F            CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       F            CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       F            OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       F            CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       F            CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       F            OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       F            Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.3     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.3     Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         OCH.sub.3                                                                              OCH.sub. 3                                                                             CH                           H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3 ).sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 Cl  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 Cl  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 Cl  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 Cl  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 Br  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 Br  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 F   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(Cl)CH.sub.3                                                                              Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.3                                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH(F)CH.sub.3                                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(F)CH.sub.3                                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(F)CH.sub.3                                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(F)CH.sub.3                                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.3                                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.3                                                                               Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(F)CH.sub.2 CH.sub.3                                                                      Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 H   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CF.sub.2 H   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CF.sub.2 H   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CF.sub.2 H   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CF.sub.2 H   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 H   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CF.sub.2 H   Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       Cl.sub.2 H   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       Cl.sub.2 H   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Cl.sub. 2 H  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       Cl.sub.2 H   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       Cl.sub.2 H   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       Cl.sub.2 H   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       Cl.sub.2 H   Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH(F)CH.sub.3                                                                      CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CH(F)CH.sub.3                                                                      CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH(F)CH.sub.3                                                                      OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3)CH(Cl)CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(CH.sub.3)CH(Cl)CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 Br                                                                     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 Br                                                                     Cl      OCH.sub.3                                                                              N                            H  A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       cyclopropyl  OCH.sub. 3                                                                             OCH.sub.3                                                                              CH                           H  A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       cyclopropyl  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       cyclopropyl  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR401##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR402##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR403##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR404##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR405##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR406##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR407##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR408##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR409##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR410##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR411##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR412##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR413##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR414##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR415##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR416##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR417##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR418##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR419##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR420##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR421##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       cyclobutyl   CH      CH.sub.3                                                                               CH                           H  A-1 -- O  H       cyclobutyl   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       cyclobutyl   OCH     OCH.sub.3                                                                              CH                           H  A-1 -- O  H       cyclobutyl   CH      CH      N                            H  A-1 -- O  H       cyclobutyl   CH      OCH.sub.3                                                                              N                            H  A-1 -- O  H       cyclobutyl   OCH.sub.3                                                                              OCH     N                            H  A-1 -- O  H       cyclobutyl   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          CH.sub. 3                                                                              CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2CHCH.sub.2                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHCH.sub.2   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CHCH.sub.2   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CHCH.sub.2   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CFCH.sub.2                                                                          CH.sub.3                                                                               CH      CH                           H  A-1 -- O  H       CH.sub.2CFCH.sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHFCH.sub.2  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHFCH.sub.2  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CHFCH.sub.2  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CHFCH.sub.2  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2CCHCH.sub.3                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHCH.sub.2   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CHCH.sub.2   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CHCH.sub.2   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CHCH.sub.2   Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CCH CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CCH CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CCH OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CCH CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 CCH CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CCH OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CCH Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CCH          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       C CH         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CCH          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CCH          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CCH          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CCH          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CCCH.sub.2 F Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CCCH.sub.2 F CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CCCH.sub.2 F CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CCCH.sub.2 F OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2CCCH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2CCCH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2CCCH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2CCCH.sub.2 Cl                                                                       Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.3    CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.3    CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.3    OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.3    CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.3    CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.3    OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.3    Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub. 3                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH(CH.sub.3).sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 H  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCF.sub.2 H  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 H  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 H  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCF.sub.2 H  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCF.sub. 2 H OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCF.sub.2 H  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCF.sub.2 CH.sub. 3                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub. 2 Cl                                                                      CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Br                                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Br                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Br                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2 CH.sub.2 Br                                                                       Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CCH CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2CCH CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CCH OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CCH CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2C CH                                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CCH OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CCH Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       OCH.sub.2CHCH.sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       NO.sub.2     Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 F                                                                Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub. 2 CH.sub.2 OCH.sub.3                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 OCH.sub.3                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub. 2 OCH.sub.3                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       N(CH.sub.3 ).sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       N(CH.sub.3).sub.2                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       NCH.sub.2 CH.sub.3 (CH.sub.3).sub.2                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.3    CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SCH.sub.3    CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.3    OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.3    CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SCH.sub.3    CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.3    OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.3    Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SCH.sub.2 CH.sub.2 CH.sub.3                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.3                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.3                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                OCH.sub. 3                                                                             OCH.sub.3                                                                              N                            H  A-1 -- O  H       SOCH.sub.2 CH.sub.2 CH.sub.3                                                                Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         Cl      OCH.sub. 3                                                                             CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(CH.sub.3)CH.sub.2 CH.sub.3                                                       Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 NHCH.sub.3                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CON(CH.sub.3).sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CONHCH.sub.3 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CONHCH.sub.3 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CONHCH.sub.3 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CONHCH.sub.3 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CONHCH.sub.3 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CONHCH.sub.3 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CONHCH.sub.3 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CONHCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CON(CH.sub.2 CH.sub.3).sub.2                                                                Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR422##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR423##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR424##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR425##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR426##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR427##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR428##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR429##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR430##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR431##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR432##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR433##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR434##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR435##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR436##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR437##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR438##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR439##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR440##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR441##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR442##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR443##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR444##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR445##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR446##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR447##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR448##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR449##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR450##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR451##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR452##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR453##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR454##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR455##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR456##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR457##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR458##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR459##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR460##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR461##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR462##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR463##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR464##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR465##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR466##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR467##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR468##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR469##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR470##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR471##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H                                                                                       ##STR472##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR473##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H                                                                                       ##STR474##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H                                                                                       ##STR475##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR476##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H                                                                                       ##STR477##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.3     OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.3     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.3     Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH(CH.sub.3).sub.2                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  H       CH.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CH(CH.sub.3)CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  H       CH.sub.2 CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       cyclopropyl  Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR478##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR479##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR480##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR481##  CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR482##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR483##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR484##  Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR485##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR486##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR487##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR488##  CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR489##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR490##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR491##  Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR492##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR493##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR494##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR495##  CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR496##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR497##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H                                                                                       ##STR498##  Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 Cl                                                                       Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CH.sub.2 F                                                                        Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCH.sub.2 CF.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       OCF.sub.2 CH.sub.3                                                                          Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       NO.sub.2     Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.3                                                                  Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        CH.sub. 3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                        Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2 CHCH.sub.2                                                                Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               CH.sub. 3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       CO.sub.2 CH.sub.2CCH                                                                        Cl      OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            CH.sub.3                                                                          A-1 -- O  H       N(CH.sub.3).sub.2                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-F     CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH.sub.3     OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH.sub.3     CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-F     CH.sub.3     CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     CH.sub.3     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     CH.sub.3     Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-F     CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-F     CH.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     CH.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     CH.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-F     CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH(CH.sub.3).sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-F     CH(CH.sub.3).sub.2                                                                          CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     CH(CH.sub.3).sub.2                                                                          OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     CH(CH.sub.3).sub.2                                                                          Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH.sub.2 CH.sub.2 CH.sub.2                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-F     CH.sub.2 CH.sub.2 CH.sub. 2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH(CH.sub.3)CH.sub.2 CH.sub.2                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-F     CH(CH.sub.3)CH.sub.2 CH.sub.2                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-F     CH.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     CH.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-F     CH.sub.2 CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl    cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-Cl    cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl    cyclopropyl  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl    cyclopropyl  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-Cl    cyclopropyl  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-Cl    cyclopropyl  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-Cl    cyclopropyl  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl                                                                                    ##STR499##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-Cl                                                                                    ##STR500##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl                                                                                    ##STR501##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl                                                                                    ##STR502##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-Cl                                                                                    ##STR503##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-Cl                                                                                    ##STR504##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-Cl                                                                                    ##STR505##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl                                                                                    ##STR506##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-Cl                                                                                    ##STR507##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl                                                                                    ##STR508##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl                                                                                    ##STR509##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-Cl                                                                                    ##STR510##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-Cl                                                                                    ##STR511##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-Cl                                                                                    ##STR512##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl                                                                                    ##STR513##  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-Cl                                                                                    ##STR514##  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl                                                                                    ##STR515##  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-Cl                                                                                    ##STR516##  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-Cl                                                                                    ##STR517##  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-Cl                                                                                    ##STR518##  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-Cl                                                                                    ##STR519##  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 CH.sub.2 F                                                               Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Cl                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Cl                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Br                                                                       CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Br                                                                       CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Br                                                                       OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2 CH.sub.2 Br                                                                       Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CCH CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CCH CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CCH OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CCH CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2C CH                                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CCH OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CCH Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             OCH.sub.2CHCH.sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-CH.sub.3                                                                             NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             NO.sub.2     CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-CH.sub.3                                                                             NO.sub.2     CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             NO.sub.2     OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             NO.sub.2     Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub. 2 CH.sub.3                                                        CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-CH.sub.3                                                                             CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH(CH.sub.3).sub.2                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub. 2 Cl                                                              CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                               Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 CH.sub.2 F                                                                Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  5-OCH.sub.2 CF.sub.3                                                                   CO.sub.2 CH.sub.2 OCH.sub.3                                                                 Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-OCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-OCH.sub.3                                                                            CO.sub.2 CO.sub.2 CH.sub.3                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-OCH.sub.3                                                                            SO.sub.2 N(CH.sub.3).sub.2                                                                  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-OCH.sub. 3                                                                           SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-OCH.sub.3                                                                            SO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-F     SCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-F     SCH.sub.2CHCH.sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     SCH.sub.2CHCH.sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     SCH.sub.2CHCH.sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SCH.sub.2 CH.sub.2 OCH.sub.3                                                                CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-F     SCH.sub.2CCH CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SCH(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-F     SCH(CH.sub.3).sub.2                                                                         CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     SCH(CH.sub.3).sub.2                                                                         OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     SCH(CH.sub.3).sub.2                                                                         Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SOCH.sub.3   CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-F     SOCH.sub.3   CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SOCH.sub.3   OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SOCH.sub.3   CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-F     SOCH.sub.3   CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     SOCH.sub.3   OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     SOCH.sub. 3  Cl      OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               CH                           H  A-1 -- O  6-F     SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              CH                           H  A-1 -- O  6-F     SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                                                                               N                            H  A-1 -- O  6-F     SO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     SO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                                                                              N                            H  A-1 -- O  6-F     SO.sub.2 CH.sub.3                                                                           Cl      OCH.sub.3                                                                              CH                           __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.1 Y.sub.1      m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               O                                    H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.2                             H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              O                                    H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CH.sub.2                             H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.2 CH.sub.3                                                                     O                                    H  A-2 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            CH.sub.2                             H  A-2 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                               O                                    H  A-2 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  OCH.sub.3                                                                              O                                    H  A-2 -- O  H       SO.sub.2 N(CH.sub.3).sub.2                                                                  OCF.sub.2 H                                                                            CH.sub.2                             __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.1              m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-3 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                     H  A-3 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                    H  A-3 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.2 CH.sub.3                           H  A-3 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                  H  A-3 -- O  H       Cl           CH.sub.3                                     H  A-3 -- O  H       Cl           OCH.sub.3                                    H  A-3 -- O  H       SO.sub.2 CH.sub.3                                                                           CH.sub.3                                     H  A-3 -- O  H       SO.sub.2 CH.sub.3                                                                           OCH.sub.3                                    __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.1 Y.sub.3      m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               H                                    H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              H                                    H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.2 CH.sub.3                                                                     H                                    H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            H                                    H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                             H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CH.sub.3                             H  A-4 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            CH.sub.3                             __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.2 Y.sub.2      m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                            H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.2 CH.sub.3                   H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.2 CH.sub.3                                                                     SCH.sub.3                            H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            SCH.sub.3 CH.sub.3                   H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                             H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.2 CH.sub.3                    H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 CH.sub.3                                                                      OCH.sub.3                            H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 CH.sub.3                                                                      SCH.sub.3                            H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                   H  A-5 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 CF.sub.3                                                                      OCH.sub.3                            __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.3              m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-6 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                     H  A-6 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                    H  A-6 -- O  H       NO.sub.2     CH.sub.3                                     H  A-6 -- O  H       NO.sub.2     OCH.sub.3                                    __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X.sub.4 Y.sub.4      m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.3                             H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                            H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.2 CH.sub.3                   H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               Cl                                   H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CH.sub.3                             H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.3                            H  A-7 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.2 CH.sub.3                                                                     OCH.sub.3                            __________________________________________________________________________     R  A   E  W  R.sub.1 R.sub.2      X       Y       Z    m.p.                    __________________________________________________________________________                                                            (°C.)            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCF.sub.2 H                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               SCF.sub.2 H                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               SCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               NHCH.sub.3                                                                             N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               N(CH.sub.3).sub.2                                                                      N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               CCH     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                               cyclopropyl                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CN      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CH.sub.2 CH.sub.3                                                                      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              SCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              OCF.sub.2 H                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              N(CH.sub.3).sub.2                                                                      N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              NHCH.sub.3                                                                             N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCH.sub.3                                                                              CN      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            CH.sub.2 CH.sub.3                                                                      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            SCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            N(CH.sub.3).sub.2                                                                      N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           OCF.sub.2 H                                                                            NHCH.sub.3                                                                             N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     CH.sub.3                                                                               CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     CH.sub.2 Cl                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                     CH.sub.2 Br                                                                            CH                           H  A-1 -- O  H       CO.sub. 2 CH.sub.3                                                                          SCF.sub.2 H                                                                            OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           SCF.sub.2 H                                                                            CH.sub.2 CH.sub.3                                                                      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           SCF.sub.2 H                                                                            CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           SCF.sub.2 H                                                                            NHCH.sub.3                                                                             N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           N(CH.sub.3).sub.2                                                                      OCH.sub.2 CH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           N(CH.sub.3).sub.2                                                                      CH.sub.2 CH.sub.3                                                                      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           N(CH.sub.3).sub.2                                                                      CH.sub.2 F                                                                             CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           N(CH.sub.3).sub.2                                                                      CH.sub.2 OCH.sub.3                                                                     CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           N(CH.sub.3).sub.2                                                                      cyclopropyl                                                                            CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CCH     CH.sub.2 CH.sub.3                                                                      CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CCH     OCH.sub.3                                                                              CH                           H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CCH     N(CH.sub.3).sub.2                                                                      N                            H  A-1 -- O  H       CO.sub.2 CH.sub.3                                                                           CCH     OCH.sub.2 CH.sub.3                                                                     N                            __________________________________________________________________________

Formulations

Useful formulations of the compounds of Formula I can be prepared in conventional ways. They include dusts, granules, pellets, solutions, suspensions, emulsions, wettable powders, emulsifiable concentrates and the like. Many of these may be applied directly. Sprayable formulations can be extended in suitable media and used at spray volumes of from a few liters to several hundred liters per hectare. High strength compositions are primarily used as intermediates for further formulation. The formulations, broadly, contain about 0.1% to 99% by weight of active ingredient(s) and at least one of (a) about 0.1% to 20% surfactant(s) and (b) about 1% to 99.9% solid or liquid inert diluent(s). More specifically, they will contain these ingredients in the following approximate proportions:

    ______________________________________                                                     Weight Percent*                                                                Active                                                                         Ingredient                                                                             Diluent(s)                                                                               Surfactant(s)                                    ______________________________________                                         Wettable Powders                                                                             20-90     0-74      1-10                                         Oil Suspensions,                                                                             3-50      40-95     0-15                                         Emulsions Solutions                                                            (including Emulsifiable                                                        Concentrates)                                                                  Aqueous Suspension                                                                           10-50     40-84     1-20                                         Dusts         1-25      70-99     0-5                                          Granules and Pellets                                                                         0.1-95    5-99.9    0-15                                         High Strength 90-99     0-10      0-2                                          Compositions                                                                   ______________________________________                                          *Active ingredient plus at least one of a Surfactant or a Diluent equals       100 weight percent.                                                      

Lower or higher levels of active ingredient can, of course, be present depending on the intended use and the physical properties of the compound. Higher ratios of surfactant to active ingredient are sometimes desirable, and are achieved by incorporation into the formulation or by tank mixing.

Typical solid diluents are described in Watkins, et al., "Handbook of Insecticide Dust Diluents and Carriers", 2nd Ed., Dorland Books, Caldwell, N.J., but other solids, either mined or manufactured, may be used. The more absorptive diluents are preferred for wettable powders and the denser ones for dusts. Typical liquid diluents and solvents are described in Marsden, "Solvents Guide," 2nd Ed., Interscience, New York, 1950. Solubility under 0.1% is preferred for suspension concentrates; solution concentrates are preferably stable against phase separation at 0° C. "McCutcheon's Detergents and Emulsifiers Annual", MC Publishing Corp., Ridgewood, N.J., as well as Sisely and Wood, "Encyclopedia of Surface Active Agents", Chemical Publishing Co., Inc., New York, 1964, list surfactants and recommended uses. All formulations can contain minor amounts of additives to reduce foaming, caking, corrosion, microbiological growth, etc.

The methods of making such compositions are well known. Solution are prepared by simply mixing the ingredients. Fine solid compositions are made by blending and, usually, grinding as in a hammer or fluid energy mill. Suspensions are prepared by wet milling (see, for example, Littler, U.S. Pat. No. 3,060,084). Granules and pellets may be made by spraying the active material upon preformed granular carriers or by agglomeration techniques. See J. E. Browning, "Agglomeration", Chemical Engineering, Dec. 4, 1967, pp. 147ff. and "Perry's Chemical Engineer's Handbook", 5th Ed., McGraw-Hill, New York, 1973, pp. 8-57ff.

For further information regarding the art of formulation, see for example:

H. M. Loux, U.S. Pat. No. 3,235,361, Feb. 15, 1966, Col. 6, line 16 through Col. 7, line 19 and Examples 10 through 41;

R. W. Luckenbaugh, U.S. Pat. No. 3,309,192, Mar. 14, 1967, Col. 5, line 43 through Col. 7, line 62 and Examples 8, 12, 15, 39, 41, 52, 53, 58, 132, 138-140, 162-164, 166, 167 and 169-182;

H. Gysin and E. Knusli, U.S. Pat. No. 2,891,855, June 23, 1959, Col. 3, line 66 through Col. 5, line 17 and Examples 1-4;

G. C. Klingman, "Weed Control as a Science", John Wiley and Sons, Inc., New York, 1961, pp. 81-96; and

J. D. Fryer and S. A. Evans, "Weed Control Handbook", 5th Ed., Blackwell Scientific Publications, Oxford, 1968, pp. 101-103.

In the following Examples, all parts are by weight unless otherwise indicated.

EXAMPLE 9

Wettable Powder

    ______________________________________                                         N--[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino-                                                           80%                                               carbonyl]-2-pyridinesulfonamide-1-oxide                                        sodium alkylnaphthalenesulfonate                                                                            2%                                                sodium ligninsulfonate       2%                                                syntheic amorphous silica    3%                                                kaolinite                    13%                                               ______________________________________                                    

The ingredients are blended, hammer-milled until all the solids are essentially under 50 microns, reblended, and packaged.

EXAMPLE 10

Wettable Powder

    ______________________________________                                         N--[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-3-                                                          50%                                               methyl-2-pyridinesulfonamide-1-oxide                                           sodium alkylnaphthalenesulfonate                                                                             2%                                               low viscosity methyl cellulose                                                                               2%                                               diatomaceous earth           46%                                               ______________________________________                                    

The ingredients are blended, coarsely hammer-milled and then air-milled to produce particles essentially all below 10 microns in diameter. The product is reblended before packaging.

EXAMPLE 11

Granule

    ______________________________________                                          Granule                                                                       ______________________________________                                         Wettable Powder of Example 10                                                                              5%                                                 attapulgite granules       95%                                                 ______________________________________                                    

A slurry of wettable powder containing 25% solids is sprayed on the surface of attapulgite granules in a double-cone blender. The granules are dried and packaged.

EXAMPLE 12

Extruded Pellet

    ______________________________________                                         N--[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino-                                                          25%                                                carbonyl]-2-pyridinesulfonamide-1-oxide                                        anhydrous sodium sulfate    10%                                                crude calcium ligninsulfonate                                                                               5%                                                sodium alkylnaphthalenesulfonate                                                                            1%                                                calcium/magnesium bentonite 59%                                                ______________________________________                                    

The ingredients are blended, hammer-milled and then moistened with about 12% water. The mixture is extruded as cylinders about 3 mm diameter which are cut to produce pellets about 3 mm long. These may be used directly after drying, or the dried pellets may be crushed to pass a U.S.S. No. 20 sieve (0.84 mm openings). The granules held on a U.S. Ser. No. 40 sieve (0.42 mm openings) may be packaged for use and the fines recycled.

EXAMPLE 13

Low Strength Granule

    ______________________________________                                         N--[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-3-                                                          0.1%                                              methyl-2-pyridinesulfonamide-1-oxide                                           attapulgite granules        99.9%                                              (U.S.S. 20 to 40 mesh)                                                         ______________________________________                                    

The active ingredient is dissolved in a solvent and the solution is sprayed upon dedusted granules in a double-cone blender. After spraying of the solution has been completed, the material is warmed to evaporate the solvent. The material is allowed to cool and then packaged.

EXAMPLE 14

Granule

    ______________________________________                                         N--[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino-                                                           80%                                               carbonyl]-2-pyridinesulfonamide-1-oxide                                        wetting agent                 1%                                               crude ligninsulfonate salt (containing                                                                      10%                                               5 to 20% of the natural sugars)                                                attapulgite clay              9%                                               ______________________________________                                    

The ingredients are blended and milled to pass through a 100 mesh screen. This material is then added to a fluid bed granulator, the air flow is adjusted to gently fluidize the material, and a fine spray of water is sprayed onto the fluidized material. The fluidization and spraying are continued until granules of the desired size range are made. The spraying is stopped, but fluidization is continued, optionally with heat, until the water content is reduced to the desired level, generally less than 1%. The material is then discharged, screened to the desired size range, generally 14 to 100 mesh (1410 to 149 microns), and packaged for use.

EXAMPLE 15

Low Strength Granule

    ______________________________________                                         N--[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-3-                                                          1%                                                methyl-2-pyridinesulfonamide-1-oxide                                           N,N--dimethylformamide       9%                                                attapulgite granules        90%                                                (U.S.S. 20 to 40 sieve)                                                        ______________________________________                                    

The active ingredient is dissolved in the solvent and the solution is sprayed upon dedusted granules in a double cone blender. After spraying of the solution has been completed, the blender is allowed to run for a short period and then the granules are packaged.

EXAMPLE 16

Aqueous Suspension

    ______________________________________                                         N--[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino-                                                         40%                                                 carbonyl]-2-pyridinesulfonamide-1-oxide                                        polyacrylic acid thickener 0.3%                                                dodecylphenol polyethylene glycol ether                                                                   0.5%                                                disodium phosphate         1%                                                  monosodium phosphate       0.5%                                                polyvinyl alcohol          1.0%                                                water                      56.7%                                               ______________________________________                                    

The ingredients are blended and ground together in a sand mill to produce particles essentially all under 5 microns in size.

EXAMPLE 17

Solution

    ______________________________________                                         N--[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-3-                                                          5%                                                methyl-2-pyridinesulfonamide-1-oxide, ammonium                                 salt                                                                           water                       95%                                                ______________________________________                                    

The salt is added directly to the water with stirring to produce the solution, which may then be packaged for use.

EXAMPLE 18

High Strength Concentrate

    ______________________________________                                         N--[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino-                                                           99%                                               carbonyl]-2-pyridinesulfonamide-1-oxide                                        silica aerogel               0.5%                                              synthetic amorphous silica   0.5%                                              ______________________________________                                    

The ingredients are blended and ground in a hammer-mill to produce a material essentially all passing a U.S. Ser. No. 50 screen (0.3 mm opening). The concentrate may be formulated further if necessary.

EXAMPLE 19

Wettable Powder

    ______________________________________                                         N--[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-3-                                                         90%                                                methyl-2-pyridinesulfonamide-1-oxide                                           dioctyl sodium sulfosuccinate                                                                              0.1%                                               synthetic fine silica       9.9%                                               ______________________________________                                    

The ingredients are blended and ground in a hammer-mill to produce particles essentially all below 100 microns. The material is sifted through a U.S. Ser. No. 50 screen and then packaged.

EXAMPLE 20

Wettable Powder

    ______________________________________                                         N--[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino-                                                           40%                                               carbonyl]-2-pyridinesulfonamide-1-oxide                                        sodium ligninsulfonate       20%                                               montmorillonite clay         40%                                               ______________________________________                                    

The ingredients are thoroughly blended, coarsely hammer-milled and then air-milled to produce particles essentially all below 10 microns in size. The material is reblended and then packaged.

EXAMPLE 21

Oil Suspension

    ______________________________________                                         N--[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-3-                                                          35%                                               methyl-2-pyridinesulfonamide-1-oxide                                           blend of polyalcohol carboxylic                                                                              6%                                               esters and oil soluble petroleum                                               sulfonates                                                                     xylene                       59%                                               ______________________________________                                    

The ingredients are combined and ground together in a sand mill to produce particles essentially all below 5 microns. The product can be used directly, extended with oils, or emulsified in water.

EXAMPLE 22

Dust

    ______________________________________                                         N--[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino-                                                           10%                                               carbonyl]-2-pyridinesulfonamide-1-oxide                                        attapulgite                  10%                                               Pyrophyllite                 80%                                               ______________________________________                                    

The active ingredient is blended with attapulgite and then passed through a hammer-mill to produce particles substantially all below 200 microns. The ground concentrate is then blended with powdered pyrophyllite until homogeneous.

EXAMPLE 23

Oil Suspension

    ______________________________________                                         N--[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-3-                                                          25%                                               methyl-2-pyridinesulfonamide-1-oxide                                           polyoxyethylene sorbitol hexaoleate                                                                          5%                                               highly aliphatic hydrocarbon oil                                                                            70%                                               ______________________________________                                    

The ingredients are ground together in a sand mill until the solid particles have been reduced to under about 5 microns. The resulting thick suspension may be applied directly, but preferably after being extended with oils or emulsified in water.

EXAMPLE 24

Wettable Powder

    ______________________________________                                         N--[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino-                                                           20%                                               carbonyl]-2-pyridinesulfonamide-1-oxide                                        sodium alkylnaphthalenesulfonate                                                                            4%                                                sodium ligninsulfonate       4%                                                low viscosity methyl cellulose                                                                              3%                                                attapulgite                  69%                                               ______________________________________                                    

The ingredients are thoroughly blended. After grinding in a hammer-mill to produce particles essentially all below 100 microns, the material is reblended and sifted through a U.S. Ser. No. 50 sieve 0.3 mm opening) and packaged.

Utility

Test results indicate that the compounds of the present invention are highly active preemergent or postemergent herbicides or plant growth regulants. Many of them have utility for broad-spectrum pre- and/or post-emergence weed control in areas where complete control of all vegetation is desired, such as around fuel storage tanks, industrial storage areas, parking lots, drive-in theaters, around billboards, highway and railroad structures. Some of the compounds have utility for selective weed control in crops such as wheat, barley and corn. Alternatively, the subject compounds are useful to modify plant growth.

The rates of application for the compounds of the invention are determined by a number of factors, including their use as plant growth modifiers or as herbicides, the crop species involved, the types of weeds to be controlled, weather and climate, formulations selected, mode of application, amount of foliage present, etc. In general terms, the subject compounds should be applied at levels of around 0.01 to 10 kg/ha, the lower rates being suggested for use on lighter soils and/or those having a low organic matter content, for plant growth modification or for situations where only short-term persistence is required.

The compounds of the invention may be used in combination with any other commercial herbicide, examples of which are those of the triazine, triazole, uracil, urea, amide, diphenylether, carbamate and bipyridylium, imidazolinone types.

The herbicidal properties of the subject compounds were discovered in a number of greenhouse tests. The test procedures and results follow.

    ______________________________________                                         Compounds                                                                      Compound                                                                               R.sub.1  R.sub.2    X      Y     Z                                     ______________________________________                                          ##STR520##                                                                     1               H          CH.sub.3                                                                              CH.sub.3                                                                             CH                                     2               H          CH.sub.3                                                                              OCH.sub.3                                                                            CH                                     3               H          OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                     4               H          CH.sub.3                                                                              CH.sub.3                                                                             N                                      5               H          CH.sub.3                                                                              OCH.sub.3                                                                            N                                      6               H          OCH.sub.3                                                                             OCH.sub.3                                                                            N                                      7               CH.sub.3   CH.sub.3                                                                              CH.sub.3                                                                             CH                                     8               CH.sub.3   CH.sub.3                                                                              OCH.sub.3                                                                            CH                                     9               CH.sub.3   OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                    10               CH.sub.3   CH.sub.3                                                                              OCH.sub.3                                                                            N                                     11               CH.sub.3   OCH.sub.3                                                                             OCH.sub.3                                                                            N                                     12               CH.sub.3   Cl     OCH.sub.3                                                                            CH                                    13               cyclopropyl                                                                               CH.sub.3                                                                              CH.sub.3                                                                             CH                                    14               cyclopropyl                                                                               CH.sub.3                                                                              OCH.sub.3                                                                            CH                                    15               cyclopropyl                                                                               OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                    16               cyclopropyl                                                                               OCH.sub.3                                                                             OCH.sub.3                                                                            N                                     17               CH(CH.sub.3).sub.2                                                                        CH.sub.3                                                                              CH.sub.3                                                                             CH                                    18               CH(CH.sub.3).sub.2                                                                        OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                     ##STR521##                                                                    19      SCH.sub.3                                                                               H          CH.sub.3                                                                              CH.sub.3                                                                             CH                                    20      SCH.sub.3                                                                               H          CH.sub.3                                                                              OCH.sub.3                                                                            CH                                    21      SCH.sub.3                                                                               H          OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                    22      SCH.sub.3                                                                               H          CH.sub.3                                                                              OCH.sub.3                                                                            N                                     23      SCH.sub.3                                                                               H          OCH.sub.3                                                                             OCH.sub.3                                                                            N                                     24      SCH.sub.3                                                                               H          Cl     OCH.sub.3                                                                            CH                                    25      H        OC.sub.2 H.sub.5                                                                          OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                    26      H        OC.sub.2 H.sub.5                                                                          CH.sub.3                                                                              OCH.sub. 3                                                                           N                                     27      H        OC.sub.2 H.sub.5                                                                          Cl     OCH.sub.3                                                                            CH                                    28      SCH.sub.3                                                                               SCH.sub.3  CH.sub.3                                                                              OCH.sub.3                                                                            CH                                     ##STR522##                                                                    29               CH.sub.3   OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                    30               CH.sub.3   CH.sub.3                                                                              OCH.sub.3                                                                            CH                                    31               CH.sub.3   CH.sub.3                                                                              OCH.sub.3                                                                            N                                     ______________________________________                                    

Test A

Seeds of crabgrass (Digitaria spp.), barnyard-grass (Echinochloa crusgalli), giant foxtail (Setaria faberi), wild oats (Avena fatua), cheatgrass (Bromus secalinus), velvetleaf (Abutilon theophrasti), morningglory (Ipomoea spp.), cocklebur (Xanthium pensylvanicum), sorghum, corn, soybean, sugarbeet, cotton, rice, wheat, barley and purple nutsedge (Cyperus rotundus) tubers were planted and treated preemergence with the test chemicals dissolved in a non-phytotoxic solvent. At the same time, these crop and weed species were treated with a soil/foilage application. At the time of treatment, the plants ranged in height from 2 to 18 cm. Treated plants and controls were maintained in a greenhouse for sixteen days, after which all species were compared to controls and visually rated for response to treatment. The ratings, summarized in Table A, are based on a numerical scale extending from 0=no injury, to 10=complete skill. The accompanying descriptive symbols have the following meanings:

C=chlorosis/necrosis;

B=burn;

D=defoliation;

E=emergence inhibition;

G=growth retardation;

H=formative effect;

U=unusual pigmentation;

X=axillary stimulation;

S=albinism; and

6Y=abscised buds or flowers.

A dash (--) response means no test. Response ratings are contained in Table A.

    TABLE A       CMPD 1 CMPD 2CMPD 3 CMPD 4 CMPD 5 CMPD 6 CMPD 7  CMPD 8 CMPD 9 CMPD 10      CMPD 11 RATE RATE = KG/HA 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05      0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01        POSTEMERGENCE COTTON 0 -- 4C,9G -- 4C,9G -- 0 -- 0 -- 0 -- 3C,7H 2C 9H 2      C,8G 3C,9G 2C,9H 9H 1C 4C,9H 3C,6G MORNING GLORY 2H -- 5C,9G -- 10C -- 0      -- 0 -- 1H -- 4C,8H 2C,2H 4C,9G 2C,7G 10C 9C 5C,9G 3C,8H 5C,9G 3C,8H      COCKLEBUR 0 -- 4C,9G -- 9C -- 0 -- 3C,5H --  0 -- 4C,8G 2C,4G 8G 2C,7G      10C 7G 4C,9H 6G 6H 3G NUTSEDGE 0 -- 2C,9G -- 5C,9G -- 0 -- 0 -- 0 --      4C,8G 0 9G 8G 4C,9G 9G 2G 0 0 0 CRABGRASS 0 -- 2G -- 2C,8G -- 0 -- 0 --      2G -- 7G 0 8G 5G 4C,9G 3C,7G 2C,8G 3G 0 0 BARNYARD GRASS 0 -- 4C,9H --      9C -- 0 -- 3C,8H -- 2C,8H -- 3C,9H 3C,6H 5C,9G 4C,9H 10C 4C,9H 9C 3C,7H      5C,9G 3C,7H WILD OATS -- -- -- -- -- -- -- -- -- -- -- -- 2G 0 6G 3C,6G      2C,8G 5G 3G 0 1C 0 WHEAT 0 -- 2C,3G -- 4C,9G -- 0 -- 0 -- 2G -- 7G 4G 7G      5G 4C,9G 4C,9G 9G 0 7G -- CORN 0 -- 9C -- 4C,9G -- 0 -- 3C,9H -- 4H --      3C,7G 1C,3G 4C,9G 2C,9G 9C 3C,9G 9C 4C,9G 5C,9G 4C,9G SOYBEAN 0 --      5C,9G -- 5C,9G -- 0 -- 2C,7G -- 2C,4G -- 3C,9H 3C,3H 5C,9G 3C,8G 5C,9G      3C,9G 5C,9G 2C,4G 5C,9G 2C,2H RICE 6G -- 9C -- 9C -- 0 -- 5C,9G -- 5C,9G      -- 5C,9G 3C,8G 5C,9G 3C,9G 5C,9G 5C,9G 6C,9G 4C,9G 5C,9G 4C,9G SORGHUM      2G -- 9G -- 4C,9G -- 0 -- 3C,9H -- 3C,8H -- 4C,9G 2C,5G 3C,9G 3C,8G      3C,9G 5C,9G 5C,9G 4C,9H 4C,9G 3C,9G CHEATGRASS 0 -- 4C,8G -- 5C,9G -- 0      -- 2C,4G -- 2C,4G -- 9G 5G 9G 7G 9C 4C,9G 3C,7G 2C,5G 8G 0 SUGAR BEETS      1H -- 9C -- 9C -- 2H -- 2H -- 4H -- 4C,9G 3C,7H 10C 5C,9G 9C 9C 5C,9H      3C,5H 9C 4C,9G VELVETLEAF 0 -- 5C,9G -- 9C -- 0 -- 1C -- 1C -- 4C,9H      3C,3H 9C 4C,9G 9C 9C 4C,9H 3C,7H 4C,9H 3C,6H GIANT FOXTAIL -- -- -- --      -- -- -- -- -- -- -- -- 3C,7G 2G 4C,9G 3C,7H 5C,9G 4C,9G 3C,7G 2C,3G 0 0      BARLEY -- -- -- -- -- -- -- -- -- -- -- -- -- 5G 8G -- 9C 3C,8G 9C 2G 3G      -- PREEMERGENCE COTTON -- -- -- -- -- -- -- -- -- -- -- -- 0 0 2G 0 7G      3G 2G 0 0 0 MORNING GLORY -- -- -- -- -- -- -- -- -- -- -- -- 0 0 0 0 7G      3C,3H 1H 0 0 0 COCKLEBUR -- -- -- -- -- -- -- -- -- -- -- -- 0 0 1C 0      3C,3G 2C,2H 3G 0 2G 0 NUTSEDGE -- -- -- -- -- -- -- -- -- -- -- -- -- 0      0 0 2C,3G 3G 0 0 0 0 CRABGRASS -- -- -- -- -- -- -- -- -- -- -- -- 0 0      3G 0 4G 2G 0 0 0 0 BARNYARD GRASS -- -- -- -- -- -- -- -- -- -- -- -- 0      0 2G 0 3C,8H 2G 2C,3G 0 0 0 WILD OATS -- -- -- -- -- -- -- -- -- -- --      -- 0 0 0 0 3G 0 0 0 0 0 WHEAT -- -- -- -- -- -- -- -- -- -- -- -- 0 0 0      0 0 0 0 0 0 0 CORN -- -- -- -- -- -- -- -- -- -- -- -- 0 0 0 0 3C,5G 4G      0 0 0 0 SOYBEAN -- -- -- --  -- -- -- -- -- -- -- -- 2G 0 2C 0 2C,6G 2H      0 0 1C 0 RICE -- -- -- -- -- -- -- -- -- -- -- -- 2G 0 0 0 3C,8G 3G 0 0      0 0 SORGHUM -- -- -- -- -- -- -- -- -- -- -- -- 3C 0 3C 0 3C,8G 3C,5G 3G      0 3C,3G 0 CHEATGRASS -- -- -- -- -- -- -- -- -- -- -- -- 0 0 0 0 8G 5G 0      0 0 0 SUGAR BEETS -- -- -- -- -- -- -- -- -- -- -- -- 5H 0 1H 0 2C,6H 2H      5G 3G 3H 0 VELVETLEAF -- -- -- -- -- -- -- -- -- -- -- -- 2C 0 2C 0 7G      7H 2C 0 2C 0 GIANT FOXTAIL -- -- -- -- -- -- -- -- -- -- -- -- 0 0 6G 0      3C,6G 0 0 0 0 0 BARLEY -- -- -- -- -- -- -- -- -- -- -- -- 0 0 0 0 2G 0      0 0 0 0        CMPD 12 CMPD 13 CMPD 14 CMPD 15 CMPD 16 CMPD 17 CMPD 18 CMPD 19 CMPD      20 CMPD 21 RATE RATE = KG/HA 0.050.01 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0      .05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05        POSTEMERGENCE COTTON 3C,8G 3G 2C,4G 3C,7G 6G 9G 2C,6G 3C,9H 2C,5G      4C,9G 2C,4G 2C,7H 3C,9G 5C,9G 0 0 6G 2G 2C,2G 3C,6G MORNING GLORY 4C,8G      2C,6G 1H 2C,7G 3C,6G 4C,9G 3C,8G 9C 4C,9G 9C 3C,7G 2C,8G 1C 10C 0 0      2C,3H 2C,4G 1C 3C,7G COCKLEBUR 7G 1C 2C,5G 9C 10C 4C,8H 10C 10C 9C 10C      2C,7G 3C,9H 5C,9H 10C 0 0 3C,5G 4C,9G 3C,8H 3C,9H NUTSEDGE 4C,8G -- 6G      3C,5G 7G 3C,8G 10C 9C 7G 8G 0 7G 9G 3C,9G 0 0 0 2C,8G 5G 5C,9G CRABGRASS      0 0 6G 6G 4G 6G 5G 9C 3C,7G 10C 0 2G 5G 8G 0 0 0 5G 0 4C,8G BARNYARD      GRASS 3C,9H 5H 10C 5C,9H 9H 9C 10C 9C 5C,9H 10C 4C,8H 5C,9H 4C,9H 9C 0 0      0 0 0 3C,5G WILD OATS 0 0 3C,7G 4C,9G 3C,7G 2C,9G 2C,9G 5C,9G 5C,9G 9C      9G 4C,9G 3C,9G 5C,9G 0 0 0 0 0 0 WHEAT 0 0 8G 9G 8G 3C,9G 2C,9G 5C,9G      5C,9G 9C 9G 3C,9G 9G 5C,9G 0 0 0 8G 0 3G CORN 3C,7G 2G 3C,9G 3C,9G 2C,9G      9C 3C,9G 10C 9C 9C 3C,8H 8G 3C,9G 6U,9G 0 0 0 4C,9H 3C,7G 3C,9G SOYBEAN      3H 0 4C,8G 5C,9G 4C,9G 9C 5C,9G 9C 5C,9G 9C 3C,8G 5C,9G 5C,9G 5C,9G 0 0      2H 3C,8G 2C,4H 4C,9H RICE 5C,9G 3C,6G 5C,9G 9C 9G 9C 9C 9C 9C 9C 8G      5C,9G 4C,9G 5C,9G 0 0 0 3C,5G 2G 5C,9G SORGHUM 4C,9H 3C,7H 2C,9G 4C,9G      3C,9G 3C,9G 9C 9C 3C,9G 9C 3C,8H 3C,9G3C,9G 6C,9G 0 0 3G 4C,9H 7G 3C,9H      CHEATGRASS 2C,5G 0 8G 9C 3C,7G 5C,9G 9C 9C 5C,9G 9C 9G 9G 4C,9G 9C 0 0 0      2C,8G 3G 2C,9G SUGAR BEETS 9C 4C,8G 5C,9G 5C,9G 9C 5C,9G 5C,9G 10C 9C      10C 3C,8H 3C,8H 3C,8G 10C 0 0 3C,6H 10C 5C,9G 9C VELVETLEAF 8H 2C,5G      3C,9G 10C 10C 4C,9G 10C 10C 5C,9H 5C,9H 3C,8H 5C,9G 5C,9H 4C,9G 0 0      3C,5G 4C,9G 3C,7H 5C,9G GIANT FOXTAIL 2C,5G 3G 3C,5G 9G 3C,6G 2C,8G      4C,8G 9C 3C,7G 9C 0 0 3C,9G 9C 0 0 0 3C,6G 0 3C,5G BARLEY 0 0 3C,7G      2C,9G 3C,7G 3C,8G 2C,9G 5C,9G 9G 9C 7G 9G 2C,8G 3C,8G 0 0 0 0 00      PREEMERGENCE COTTON 5G 0 0 3G 0 3G  3G 2G 6G 0 3G 4G 9G 0 0 0 0 0 0      MORNING GLORY 3G 0 0 0 0 2G 0 2G 2C,2G 8G 0 0 0 9G 0 0 0 0 0 0 COCKLEBUR      3G -- 0 0 0 0 3G 2C,5H 1C 2C,2H 0 0 8G 9H 0 0 0 1C 0 3C NUTSEDGE 0 0 0 0      0 0 9G 10E 0 0 0 0 5G 10E 0 0 0 0 0 0 CRABGRASS 0 0 0 0 0 0 2G 3C,6G 0      3C,5G 0 0 7G 8G 0 0 0 0 0 0 BARNYARD GRASS 3G 0 0 2G 0 2G 3G 9H 0 3C,8G      0 0 3C,8H 9H 0 0 0 0 0 0 WILD OATS 0 0 0 3G 0 2G 7G 3C,8G 0 3C,6G 0 0 3G      8G 0 0 0 0 0 0 WHEAT 0 0 0 5G 0 3G 8G 2C,8H 3G 8G 0 0 8G 9G 0 0 0 0 0 0      CORN 3G 0 0 2C,4G 0 3C,4G 3C,6G 3C,9G 3C,5G 3C,7G 0 2C,3G 3C,8H 9G 0 0 0      0 0 2C,3G SOYBEAN 2G 0 0 3C,4H 0 1C 3C,7G 3C,8G 2C,4G 4C,8G 0 1C 1C,3G      4C,8H 0 0 0 0 0 2C RICE 6G 0 0 3C,7G 0 0 9H 10H 3G 4C,9G 0 2C 2C,8G 10H      0 0 0 0 0 0 SORGHUM 3C,6G 0 0 3C,5G 0 2C,3G 3C,9H 9H 3C,5G 3C,9G 0 1C,2G      9G 5C,9H 0 0 0 0 2C 2C,4G CHEATGRASS 0 0 0 6G 0 3G 7G 9H 0 3C,8G 0 0 7G      4C,9H 0 0 0 0 0 0 SUGAR BEETS 0 0 0 2H 0 4G 8G 9G 5G 3C,6G 0 1C,3G 2G 9G      0 0 0 2G 2H 3H VELVETLEAF 2G 0 0 7H 4G 3H 8G 4C,9G 0 2C,5H 0 2C,3H 8G      4C,9G 0 0 0 0 0 0 GIANT FOXTAIL 0 0 0 0 0 0 7G 9H 0 2C,2G 0 0 2C,8G      3C,9G 0 0 0 0 0 0 BARLEY 0 0 0 2G 0 0 6G 3C,8G 2C,2G 8G 0 3G 9G 9G 0 0 0      0 0 0        CMPD 22 CMPD 23 CMPD 24 CMPD 25 CMPD 26 CMPD 27 CMPD 28 CMPD 29 CMPD      30 CMPD 31 RATE = KG/HA 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01      0.05 0.01  0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05        POSTEMERGENCE COTTON 0 0 0 3C,4G 0 0 2G 5C,9G 0 3C,5G 4G 3C,6G 0 0 0 0 0       0 0 0 MORNING GLORY 0 3C,6G 0 1H 0 0 9C 10C 3C,6G 4C,8G 3C,5G 5C,9G      2C,5G 3C,8H 0 0 0 0 2H 3H COCKLEBUR 3H 3C,8G 2H 3C,8H 0 3G 3C,9G 10C 7G      4C,8H 4G 4C,9G 3C,8H 5C,9G 0 0 0 0 0 0 NUTSEDGE 0 0 0 0 0 0 10C 10C 0 0      4G 5C,9G 3G  0 0 0 0 0 0 CRABGRASS 0 0 0 2G 0 0  3C,7G 0 4C,8G 3G 3C,6G      0 3G 0 0 0 0 0 0 BARNYARD GRASS 0 3G 0 2G 0 0 5C,9G 10C 3C,9H 10C 3C,7H      5C,9G 0 3C,7H 0 0 0 0 0 0 WILD OATS 0 0 0 0 0 0 3C,9G 5C,9G 3C,5G 5C,9G      0 5G 0 3G 0 0 0 0 0 0 WHEAT 0 0 0 0 0 0 8G 5C,9G 3C,6G 4C,9G 0 5G 0 3G 0      0 0 0 0 0 CORN 0 4G 0 0 0 3G 9C 10C 9C 9C 9G 9C 0 3C,9G 0 0 0 0 0 0      SOYBEAN 0 3C,3H 0 3C,4H 0 0 9C 5C,9G 3C,8G 5C,9G 5G 4C,9G 1H 3C,7H 0 0 0      0 0 0 RICE 0 3C,4G 0 4G 0 0 4C,9G 5C,9G 9C 5C,9G 4C,9G 5C,9G 0 8G 0 0 0      0 0 0 SORGHUM 0 3C,7G 0 2G 0 4G 9C 10C 5C,9G 9C 4C,9G 5C,9G 2G 3C,9G 0      2G 0 0 0 0 CHEATGRASS 0 0 0 0 0 0       3G 2G 0 9C 0 0 0 0 SUGAR BEETS      3C,4G 9C 0 5C,9G 0 3C,8H 9C 5C,9G 4C,9H 4C,8H 3C,8G 9C 3C,5G 9C 2G 10C 0      0 0 0 VELVETLEAF 0 3C,6G 0 3C,8G 0 0 5C,9G 9C 0 3C,6G 3C,7G 9C 2G 4C,9G      0 0 0 0 0 0 GIANT FOXTAIL 0 0 0 3G 0 0 9C 9C 0 0 0 0 0 2G 0 0 0 0 0 0      BARLEY 0 0 0 0 0 0 4C,9G 9C 7G 4C,9G 3G 5G 0 3G 0 5G 0 0 0 0 DOWNY BROME            4C,9G 3C,9G 7G 3C,5G 0 7G PREEMERGENCE COTTON 0 0 0 0 0 0 0 7G 0 0 5      G 5G 0 0 0 0 0 0 0 0 MORNING GLORY 0 0 0 0 0 0 7G 9G 0 0 3G 8G 0 0 0 0 0      0 0 0 COCKLEBUR 0 0 0 0 0 0 6G 3C,8H 0 0 1H 3C,7G 0 0 0 0 0 0 0 0      NUTSEDGE 0 0 0 0 0 0 10E 10E 0 0 0 9G 0 0 0 0 0 0 0 0 CRABGRASS 0 0 0 0      0 0 3C,6G 3C,9G 0 2G 2G 3C,7G 0 0 0 0 0 0 0 0 BARNYARD GRASS 0 0 0 0 0 0      3C,5G 9H 0 3C,7H 2C 7G 0 0 0 0 0 0 0 0 WILD OATS 0 0 0 0 0 0 3C,3G 3C,8H      0 0 0 0 0 0 0 0 0 0 0 0 WHEAT 0 0 0 0 0 0 2C,6G 9H 0 0 0 0 0 0 0 0 0 0 0      0 CORN 0 0 0 0 0 0 3C,7H 3C,9G 0 0 2G 3C,8G 0 0 0 0 0 0 0 0 SOYBEAN 0 0      0 0 0 0 3C,8G 3C,8H 0 0 2G 3C,6H 0 0 0 0 0 0 0 0 RICE 0 0 0 0 0 0 8H 9H      0 0 3G 9H 0 0 0 0 0 0 0 0 SORGHUM 0 0 0 0 0 0 3C,8H 10H 0 3C,8H 5G 3C,9G      0 0 0 0 0 0 0 0 CHEATGRASS 0 0 0 0 0 0       0 0 0 0 0 0 0 0 SUGAR BEETS      0 0 0 0 0 0 8G 7G 0 2H 4G 5G 0 0 0 0 0 0 0 0 VELVETLEAF 0 0 0 0 0 0 6H      3C,9G 0 0 0 2C,4H 0 0 0 0 0 0 0 0 GIANT FOXTAIL 0 0 0 0 0 0 3C,5G 3C,9H      0 0 0 2G 0 0 0 0 0 0 0 0 BARLEY 0 0 0 0 0 0 3C,6G 2C,8G 0 0 0 2G 0 0 0 0      0 0 0 0 DOWNY BROME       8G 3C,8H 0 0 2G 5G           Test B

Postemergence

Three round pans (25 cm diameter by 12.5 cm deep) were filled with Sassafras sandy loam soil. One pan was planted with nutsedge (Cyperus rotundus) tubers, crabgrass (Digitaria sanguinalis), sicklepod (Cassia obtusifolia), jimsonweed (Datura stramonium), velvetleaf (Abutilon theophrasti), lambsquarters (Chenopodium album), rice (Oryza sativa) and teaweed (Sida spinosa). The second pot was planted with green foxtail (Setaria viridis), cocklebur (Xanthium pensylvanicum), morningglory (Ipomoea hederacea), cotton (Gossypium hirsutum), johnsongrass (Sorghum halepense), barnyardgrass (Echinochloa crusgalli), corn (Zea mays), soybean (Glycine max) and giant foxtail (Setaria faberi). The third pot was planted with wheat (Triticum aestivum), barley (Hordeum vulgare), wild buckwheat (Polgonum convolvulus L.), cheatgrass (Bromus secalinus L.), sugarbeet (Beta vulgaris), wild oat (Avena fatua), viola (Viola arvensis), blackgrass (Alopecurus myosuroides), and rape (Brassica napus). The plants were grown for approximately fourteen days, then sprayed postemergence with the chemicals dissolved in a non-phytotoxic solvent.

Preemergence

Three round pans (25 cm diameter by 12.5 cm deep) were filled with Sassafras sandy loam soil. One pan was planted with nutsedge tubers, crabgrass, sicklepod, jimsonweed, velvetleaf, lambsquarters, rice and teaweed. The second pot was planted with green foxtail, cocklebur, morningglory, cotton, johnsongrass, barnyardgrass, corn, soybean and giant foxtail. The third pot was planted with wheat, barley, wild buckwheat, cheatgrass, sugarbeet, wild oat, viola, blackgrass and rape. The three pans were sprayed preemergence with the chemicals dissolved in a non-phytotoxic solvent.

Treated plants and controls were maintained in the greenhouse for 24 days, then all rated plants were compared to controls and visually rated for plant response.

Response ratings are based on a scale of 0 to 100 where 0=no effect and 100=complete control. A dash (--) response means no test.

Response ratings are contained in Table B.

                                      TABLE B                                      __________________________________________________________________________                   CMPD 2                                                           RATE RATE = G/HA                                                                             1. 4.  16.  62.   250.                                           __________________________________________________________________________     POSTEMERGENCE                                                                  GIANT FOXTAIL -- 0   0    0.0   50                                             VELVETLEAF    -- 20  70   100.30                                                                               90                                             SUGAR BEETS   -- 50  100  100.0 50                                             CRABGRASS     -- 0   0    30.20 40                                             TEAWEED       -- 0   40   80.20 50                                             JIMSONWEED    -- 20  70   80.0  60                                             RICE          -- 20  80   100.50                                                                               90                                             COCKLEBUR     -- 0   0    0.0   0                                              COTTON        -- 30  40   100.0 0                                              SOYBEAN       -- 30  90   100.0 40                                             BARNYARD GRASS                                                                               -- 0   0    30.0  0                                              WILD OATS     -- 0   0    0.0   0                                              MORINGGLORY   -- 0   50   100.0 50                                             WHEAT         -- 0   0    0.0   0                                              CASSIA        -- 20  80   100.50                                                                               80                                             JOHNSONGRASS  -- 0   0    40.40 80                                             NUTSEDGE      -- 0   0    20.20 50                                             CORN          -- 50  100  100.0 30                                             WILD BUCKWHEAT                                                                               -- --  --   --    --                                             BLACK GRASS   -- 0   0    0.50  80                                             RAPESEED      -- 50  90   100.0 80                                             BARLEY        -- --  --   --    --                                             GREEN FOXTAIL -- --  --   --    --                                             CHEAT GRASS   -- --  --   --    --                                             BUCKWHEAT     -- --  --   --    --                                             VIOLA         -- --  --   --    --                                             LAMBSQUARTER  -- --  --   --    --                                             __________________________________________________________________________                   CMPD 3                                                           RATE RATE = G/HA                                                                             1.  4.  16.  62.  250.                                           __________________________________________________________________________     POSTEMERGENCE                                                                  GIANT FOXTAIL 0   0   0    40   --                                             VELVETLEAF    0   30  90   100  --                                             SUGAR BEETS   50  90  100  100  --                                             CRABGRASS     0   0   0    30   --                                             TEAWEED       0   0   40   70   --                                             JIMSONWEED    0   0   30   70   --                                             RICE          20  50  100  100  --                                             COCKLEBUR     0   0   20   90   --                                             COTTON        0   20  60   100  --                                             SOYBEAN       0   50  100  100  --                                             BARNYARD GRASS                                                                               0   0   30   60   --                                             WILD OATS     0   0   0    30   --                                             MORINGGLORY   0   20  60   80   --                                             WHEAT         0   0   0    0    --                                             CASSIA        0   30  80   100  --                                             JOHNSONGRASS  0   30  80   100  --                                             NUTSEDGE      0   0   40   100  --                                             CORN          30  90  100  100  --                                             WILD BUCKWHEAT                                                                               --  --  --   --   --                                             BLACK GRASS   0   0   0    40   --                                             RAPESEED      50  70  100  100  --                                             BARLEY        --  --  --   --   --                                             GREEN FOXTAIL --  --  --   --   --                                             CHEAT GRASS   --  --  --   --   --                                             BUCKWHEAT     --  --  --   --   --                                             VIOLA         --  --  --   --   --                                             LAMBSQUARTER  --  --  --   --   --                                             __________________________________________________________________________                    CMPD 3                                                          RATE RATE = G/HA                                                                              1.  4.  16. 62. 250.                                            __________________________________________________________________________     PREEMERGENCE                                                                   GIANT FOXTAIL  --  --  50  90  100                                             VELVETLEAF     --  --  30  90  90                                              SUGAR BEETS    --  --  0   70  90                                              CRABGRASS      --  --  20  50  90                                              TEAWEED        --  --  0   40  90                                              JIMSONWEED     --  --  0   40  80                                              RICE           --  --  60  90  100                                             COCKLEBUR      --  --  0   0   20                                              COTTON         --  --  0   20  60                                              SOYBEAN        --  --  0   10  80                                              BARNYARD GRASS --  --  20  50  90                                              WILD OATS      --  --  0   0   40                                              MORINGGLORY    --  --  0   0   50                                              WHEAT          --  --  0   0   0                                               CASSIA         --  --  0   80  90                                              JOHNSONGRASS   --  --  20  80  90                                              NUTSEDGE       --  --  20  70  90                                              CORN           --  --  0   10  80                                              WILD BUCKWHEAT --  --  --  --  --                                              BLACK GRASS    --  --  30  80  90                                              RAPESEED       --  --  0   0   80                                              BARLEY         --  --  --  --  --                                              GREEN FOXTAIL  --  --  --  --  --                                              CHEAT GRASS    --  --  --  --  --                                              BUCKWHEAT      --  --  --  --  --                                              VIOLA          --  --  --  --  --                                              LAMBSQUARTER   --  --  --  --  --                                              __________________________________________________________________________                    CMPD 9                                                          RATE = G/HA    0250 0062 0016 0004                                             __________________________________________________________________________     PRE                                                                            NUTSEDGE       90   60   0    0                                                TEAWEED        90   0    0    0                                                JIMSONWEED     90   0    0    0                                                VELVETLEAF     90   90   80   0                                                LAMBSQUARTER   100  70   60   0                                                RICE           100  70   50   30                                               GREEN FOXTAIL  90   70   30   0                                                COCKLEBUR      80   40   40   0                                                MORNINGGLORY   80   50   20   20                                               COTTON         90   70   20   0                                                JOHNSONGRASS   80   70   30   0                                                BARNYARD GRASS 90   40   20   0                                                GIANT FOXTAIL  90   80   0    0                                                SOYBEAN        80   50   30   0                                                CORN           50   20   0    0                                                WHEAT          30   0    0    0                                                BARLEY         30   0    0    0                                                CHEAT GRASS    80   70   0    0                                                SUGAR BEETS    90   --   50   30                                               WILD OATS      50   40   0    0                                                VIOLA          90   80   0    0                                                BLACK GRASS    80   50   0    0                                                RAPESEED       90   70   30   0                                                __________________________________________________________________________     RATE = G/HA    0250 0062 0016 0004                                             __________________________________________________________________________     POST                                                                           NUTSEDGE       100  80   60   30                                               TEAWEED        90   80   50   50                                               JIMSONWEED     100  90   70   60                                               VELVETLEAF     100  100  100  80                                               LAMBSQUARTER   100  100  100  100                                              RICE           100  100  100  50                                               GREEN FOXTAIL  100  100  80   70                                               COCKLEBUR      100  50   30   20                                               MORNINGGLORY   100  100  90   30                                               COTTON         80   70   70   20                                               JOHNSONGRASS   100  80   50   30                                               BARNYARD GRASS 100  90   80   60                                               GIANT FOXTAIL  100  80   70   50                                               SOYBEAN        100  90   80   50                                               CORN           100  90   80   60                                               WHEAT          60   40   10   0                                                BARLEY         70   60   10   0                                                CHEAT GRASS    90   80   70   60                                               SUGAR BEETS    100  100  100  60                                               WILD OATS      90   70   40   30                                               VIOLA          --   --   --   0                                                BLACK GRASS    80   70   40   40                                               RAPESEED       100  100  100  100                                              __________________________________________________________________________                     CMPD 10                                                        RATE = G/HA     0062  0016   0004                                              __________________________________________________________________________     PRE                                                                            NUTSEDGE        0     0      0                                                 TEAWEED         0     0      0                                                 JIMSONWEED      0     0      0                                                 VELVETLEAF      40    0      0                                                 LAMBSQUARTER    70    0      0                                                 RICE            40    0      0                                                 GREEN FOXTAIL   0     0      0                                                 COCKLEBUR       30    20     0                                                 MORNINGGLORY    20    20     0                                                 COTTON          0     0      0                                                 JOHNSONGRASS    0     0      0                                                 BARNYARD GRASS  0     0      0                                                 GIANT FOXTAIL   0     0      0                                                 SOYBEAN         20    0      0                                                 CORN            0     0      0                                                 WHEAT           0     0      0                                                 BARLEY          0     0      0                                                 CHEAT GRASS     20    0      0                                                 SUGAR BEETS     70    0      0                                                 WILD OATS       0     0      0                                                 VIOLA           20    0      0                                                 BLACK GRASS     0     0      0                                                 RAPESEED        0     0      0                                                 __________________________________________________________________________     RATE = G/HA     0062  0016   0004                                              __________________________________________________________________________     POST                                                                           NUTSEDGE        0     0      0                                                 TEAWEED         70    60     40                                                JIMSONWEED      100   70     50                                                VELVETLEAF      90    70     40                                                LAMBSQUARTER    100   90     80                                                RICE            100   90     90                                                GREEN FOXTAIL   90    80     40                                                COCKLEBUR       70    30     0                                                 MORNINGGLORY    80    30     30                                                COTTON          50    20     0                                                 JOHNSONGRASS    60    50     20                                                BARNYARD GRASS  100   70     30                                                GIANT FOXTAIL   90    30     20                                                SOYBEAN         90    50     50                                                CORN            80    60     20                                                WHEAT           10    0      0                                                 BARLEY          10    10     0                                                 CHEAT GRASS     60    50     40                                                SUGAR BEETS     80    80     70                                                WILD OATS       40    30     0                                                 VIOLA           --    --     70                                                BLACK GRASS     30    0      0                                                 RAPESEED        100   100    70                                                __________________________________________________________________________                  CMPD 15    CMPD 16                                                RATE = G/HA  0004                                                                               0016                                                                               0062                                                                              0004                                                                               0016                                                                               0062                                           __________________________________________________________________________     PRE                                                                            GIANT FOXTAIL    50  80     0   30                                             VELVETLEAF   60  90  100                                                                               30  50  70                                             SUGAR BEETS      90  100    30  70                                             CRABGRASS    50  70  80 0   30  60                                             TEAWEED      50  70  80 0   30  60                                             JIMSONWEED   30  50  90 0   30  50                                             RICE         90  100 100                                                                               30  50  80                                             COCKLEBUR    30  60  70 0   30  50                                             COTTON       0   20  30 0   0   30                                             SOYBEAN          30  50     0   0                                              BARNYARD GRASS                                                                              0   30  70 0   30  60                                             WILD OATS        30  50     0   30                                             MORNINGGLORY 0   30  50 0   0   30                                             WHEAT            30  60     0   30                                             CASSIA       80  90  100    50  100                                            JOHNSONGRASS 60  90  100                                                                               50  70  80                                             NUTSEDGE     30  50  100                                                                               0   0   30                                             CORN             0   60     0   30                                             WILD BUCKWHEAT   50  70     30  50                                             BLACK GRASS      80  90     50  70                                             RAPESEED         50  70     30  50                                             BARLEY           30  60     0   30                                             GREEN FOXTAIL                                                                               30  70  100                                                                               0   30  50                                             CHEAT GRASS      70  90     50  70                                             LAMBSQUARTER 100 100 100                                                                               50  80  90                                             CHICK WEED       70  80     30  60                                             __________________________________________________________________________                 CMPD 15     CMPD 16                                                RATE = G/HA 0001                                                                              0004                                                                              0016                                                                              0062                                                                              0001                                                                              0004                                                                              0016                                                                              0062                                          __________________________________________________________________________     POST                                                                           GIANT FOXTAIL                                                                              20 40 60 90 0  0  50 90                                            VELVETLEAF  60 80 90 100                                                                               30 80 90 100                                           SUGAR BEETS 0  70 100                                                                               100                                                                               0  50 100                                                                               100                                           CRABGRASS   0  20 40 60 20 40 80 100                                           TEAWEED     20 40 60 90 0  40 80 90                                            JIMSONWEED  30 40 60 100                                                                               0  30 50 70                                            RICE        60 90 90 100                                                                               80 90 100                                                                               100                                           COCKLEBUR   30 50 100                                                                               100                                                                               30 80 100                                                                               100                                           COTTON      0  0  20 30 0  30 40 90                                            SOYBEAN     40 90 100                                                                               100                                                                               50 80 100                                                                               100                                           BARNYARD GRASS                                                                             70 90 100                                                                               100                                                                               40 90 100                                                                               100                                           WILD OATS   40 90 90 100                                                                               30 90 100                                                                               100                                           MORNINGGLORY                                                                               0  40 90 90 0  60 90 100                                           WHEAT       40 50 70 100                                                                               40 50 90 100                                           CASSIA      50 90 100                                                                               100                                                                               30 85 90 100                                           JOHNSONGRASS                                                                               50 85 100                                                                               100                                                                               30 60 90 100                                           NUTSEDGE    40 90 100                                                                               100                                                                               0  0  20 40                                            CORN        80 90 100                                                                               100                                                                               90 100                                                                               100                                                                               100                                           WILD BUCKWHEAT                                                                             30 50 90 100                                                                               30 80 100                                                                               100                                           BLACK GRASS 40 90 100                                                                               100                                                                               40 70 100                                                                               100                                           RAPESEED    60 100                                                                               100                                                                               100                                                                               60 100                                                                               100                                                                               100                                           BARLEY      50 60 80 100                                                                               40 90 100                                                                               100                                           GREEN FOXTAIL                                                                              40 60 80 90 0  40 80 90                                            CHEAT GRASS 30 50 90 100                                                                               0  40 90 100                                           LAMBSQUARTER                                                                               40    100                                                                               100                                                                               0  50 70 90                                            CHICK WEED  0  30 80 100                                                                               30 70 90 100                                           __________________________________________________________________________                    CMPD 18                                                         RATE = G/HA     0001                                                                               0004 0016  0062                                            __________________________________________________________________________     PRE                                                                            VELVETLEAF     20   80   100   100                                             SUGARBEETS     30   70   100   100                                             CRABGRASS      0    20   70    80                                              TEAWEED        50   60   80    100                                             JIMSONWEED     0    20   40    80                                              RICE           40   80   80    100                                             COCKLEBUR      0    30   50    80                                              COTTON         20   30   50    100                                             SOYBEAN        0    20   40    70                                              BARNYARD GRASS 30   40   100   100                                             WILD OATS      20   40   70    90                                              MORNINGGLORY   0    0    20    50                                              WHEAT          20   40   80    90                                              CASSIA              30   70    100                                             JOHNSONGRASS   30   50   70    80                                              NUTSEDGE       0    0    30    90                                              CORN           0    20   100   100                                             WILD BUCKWHEAT 20   80   90    100                                             BLACK GRASS    40   60   80    80                                              RAPESEED       30   70   100   100                                             BARLEY         20   40   70    80                                              GREEN FOXTAIL  30   50   100   100                                             CHEAT GRASS    70   80   90    90                                              LAMBSQUARTER   20   60   70    100                                             CHICK WEED     50   70   90    90                                              __________________________________________________________________________     RATE = G/HA    0001 0004 0016  0062                                            __________________________________________________________________________     POST                                                                           GIANT FOXTAIL  20   30   80    100                                             VELVETLEAF     30   60   100   100                                             SUGARBEETS          100  100   100                                             CRABGRASS      20   40   70    80                                              TEAWEED        20   40   80    100                                             JIMSONWEED     20   40   70    90                                              RICE           50   80   100   100                                             COCKLEBUR      0    50   100   100                                             COTTON              20   50                                                    SOYBEAN        40   100  100   100                                             BARNYARD GRASS 60   90   100   100                                             WILD OATS           70   90    90                                              MORNINGGLORY   0    20   80    100                                             WHEAT          50   80   100   100                                             CASSIA         40   90   100   100                                             JOHNSONGRASS   30   90   100   100                                             NUTSEDGE       20   100  100   100                                             CORN           80   90   100   100                                             WILD BUCKWHEAT 30   40   100   100                                             BLACK GRASS         60   100   100                                             RAPESEED            100  100   100                                             BARLEY         40   80   90    100                                             GREEN FOXTAIL  30   50   100   100                                             CHEAT GRASS    50   70   100   100                                             LAMBSQUARTER   30   60   80    100                                             CHICK WEED          50   70    80                                              __________________________________________________________________________ 

What is claimed is:
 1. A compound of the formula: ##STR523## wherein J is ##STR524## wherein R is H or CH₃ ;E is a single bond or CH₂ ; W is O, S or NR_(x) ; R_(x) is H, C₁ -C₃ alkyl or C₁ -C₃ alkoxy; R₁ is H, F, Cl, Br, C₁ -C₃ alkyl, C₁ -C₃ haloalkyl, C₁ -C₃ alkoxy, C₁ -C₃ haloalkoxy or C₁ -C₃ thioalkyl; R₂ is H, Cl, Br, F, C₁ -C₄ alkyl, C₁ -C₄ haloalkyl, cyclopropyl optionally substituted by 1-4 halogen, cyclobutyl optionally substituted by 1-4 halogen, C₂ -C₄ alkenyl optionally substituted by halogen, C₂ -C₄ alkynyl optionally substituted by halogen, C₁ -C₄ alkoxy, C₁ -C₄ haloalkoxy, C₃ -C₄ alkenyloxy, C₃ -C₄ alkynyloxy, NO₂, CO₂ R₃, NR₄ R₅, S(O)_(n) R₆, SO₂ NR₇ R₈, C(O)NR₉ R₁₀, ##STR525## n is 0, 1 or 2; R₃ is C₁ -C₃ alkyl, C₂ -C₃ haloalkyl, C₁ -C₃ alkoxy, C₃ -C₄ alkenyl, CH₂ (C₃ -C₅ cycloalkyl) or C₃ -C₄ alkynyl; R₄ is H or C₁ -C₂ alkyl;R₅ is C₁ -C₂ alkyl; R₆ is C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₂ -C₄ alkoxyalkyl or C₁ -C₃ haloalkyl; R₇ is H or C₁ -C₂ alkyl; R₈ is C₁ -C₂ alkyl or C₁ -C₂ alkoxy; R₈ is C₁ -C₂ alkyl or C₁ -C₂ alkoxy; R₉ is H or C₁ -C₃ alkyl; R₁₀ is C₁ -C₃ alkyl; R₁₁ is H or CH₃ ; R₁₂ is H or CH₃ ; R₁₃ is H, C₁ -C₃ alkyl, allyl, C₁ -C₃ haloalkyl or C₁ -C₃ alkyl substituted with C₁ -C₂ alkoxy; R₁₃ ' is H, C₁ -C₃ alkyl, C₁ -C₃ haloalkyl, allyl, C₁ -C₂ alkoxy, C₁ -C₂ haloalkoxy or C₁ -C₂ alkylthio; R₁₃ " is H, C₁ -C₃ alkyl, allyl or C₁ -C₃ haloalkyl; R₁₄ is C₁ -C₃ alkyl, CH₂ OCH₃ or CH₂ CN; ##STR526## X is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₂ -C₄ haloalkoxy, C₁ -C₄ haloalkyl, C₁ -C₄ haloalkylthio, C₁ -C₄ alkylthio, C₂ -C₅ alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁ -C₃ alkylamino or di(C₁ -C₃ alkyl)amino: Y is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₂ -C₄ haloalkoxy, C₁ -C₄ haloalkylthio, C₁ -C₄ alkylthio, C₂ -C₅ alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁ -C₃ alkylamino, di(C₁ -C₃ alkyl)amino, C₃ -C₄ alkenyloxy, C₃ -C₄ alkynyloxy, C₂ -C₅ alkylthioalkyl, C₂ -C₅ alkylsulfinylalkyl, C₂ -C₅ alkylsulfonylalkyl, C₁ -C₄ haloalkyl, C₂ -C₄ alkynyl, C₃ -C₅ cycloalkyl, azido, cyano. ##STR527## m is 2 or 3; Q₁ and Q₂ are independently O or S; R_(a) is H or C₁ -C₃ alkyl; R_(b) and R_(c) are independently C₁ -C₃ alkyl; Z is N; and X₃ is CH₃ or OCH₃ ;and their agriculturally suitable salts; provided that (1) when W is S, then R is H, E is a single bond, A is A-1, and Y is CH₃, OCH₃, OC₂ H₅, CH₂ OCH₃, C₂ H₅, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, OCH₂ CH₂ OCH₃, CH(OCH₃)₂ or ##STR528## and (2) when the total number of carbon atoms of X and Y is greated than four, then the combined number of carbons of R₁ and R₂ is less than or equal to six.
 2. A compound of claim 1 whereX is C₁ -C₂ alkyl, C₁ -C₂ alkoxy, CH₂ F, CF₃, OCH₂ CH₂ F, OCH₂ CHF₂, OCH₂ CF₃, CH₂ Cl or CH₂ Br; and Y is H, C₁ -C₂ alkyl, C₁ -C₂ alkoxy, CH₂ OCH₃, CH₂ OCH₂ CH₃, NHCH₃, N(OCH₃)CH₃, N(CH₃)₂, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, OCH₂ CH₂ OCH₃, CH₂ SCH₃, C(O)R_(a), ##STR529## SCH₂ H, cyclopropyl, C═CH or C═CCH₃ ; and R_(a) is H or CH₃.
 3. A compound of claim 2 whereE is a single bond; W is O; and R₁ is H, F, Cl, Br, CH₃, C₁ haloalkyl or OCH₃.
 4. A compound of claim 2 whereE is CH₂ ; W is O; and R₁ is H, F, Cl, Br, CH₃ or OCH₃.
 5. A compound of claim 3 whereR₂ is H, Cl, Br, F, C₁ -C₂ alkyl, C₁ -C₂ haloalkyl, cyclopropyl, C₁ -C₂ alkoxy, C₁ -C₂ haloalkoxy, CF═CFCl, CF═CFCF₃, NO₂, CO₂ R₃, NR₄ R₅, S(O)_(n) R₆, SO₂ NR₇ R₈, SO₂ N(OCH₃)CH₃, C(O)NR₉ R₁₀, R₂ -A, R₂ -B, R₂ -E, R₂ -J, R₂ -N, R₂ -Q, R₂ -R, R₂ -X, R₂ -Y, R₂ -AB, R₂ -AC or R₂ -AD; R₃ is CH₃, CH₂ CH₃, CH₂ CH₂ OCH₃ or CH₂ CH₂ Cl; R₄ is H or CH₃ ; R₆ is C₁ -C₃ alkyl, C₁ -C₃ haloalkyl or allyl; R₇ is H or CH₃ ; R₈ is C₁ -C₂ alkyl R₉ is H or CH₃ ; R₁₀ is CH₃ or CH₂ CH₃ ; R₁₃ is H, CH₃, CH₂ CH₃ or CH₂ CH₂ OCH₃ ; and R₁₃ " is H, CH₃ or CH₂ CH₃.
 6. A compound of claim 5 whereX is CH₃, OCH₃, OCH₂ CH₃, Cl, or OCH₂ CF₃ ; Y is CH₃, OCH₃, CH₂ CH₃, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.
 7. A compound of claim 6 whereJ is J₁ ; and A is A-1.
 8. A compound of claim 6 whereJ is J₂ ; and A is A-1.
 9. A compound of claim 6 whereJ is J₃ ; and A is A-1.
 10. A compound of claim 6 whereJ is J₄ ; and A is A-1.
 11. The compound of claim 1 which is N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)aminocarbonyl]-2-pyridinesulfonamide-1-oxide.
 12. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of the compound of claim 1 and at least one of the following: surfactant, solid or liquid diluent.
 13. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of the compound of claim 2 and at least one of the following: surfactant, solid or liquid diluent.
 14. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of the compound of claim 3 and at least one of the following: surfactant, solid or liquid diluent.
 15. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of the compound of claim 4 and at least one of the following: surfactant, solid or liquid diluent.
 16. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of the compound of claim 5 and at least one of the following: surfactant, solid or liquid diluent.
 17. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of the compound of claim 6 and at least one of the following: surfactant, solid or liquid diluent.
 18. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of the compound of claim 12 and at least one of the following: surfactant, solid or liquid diluent.
 19. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of the compound of claim
 1. 20. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of the compound of claim
 2. 21. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of the compound of claim
 3. 22. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of the compound of claim
 4. 23. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of the compound of claim
 5. 24. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of the compound of claim
 6. 25. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of the compound of claim
 11. 